Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8586_RS08075 Genome accession   NZ_AP026922
Coordinates   1545269..1545946 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain PZ900700038     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1540269..1550946
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8586_RS08045 (PC0038_16100) - 1540429..1541059 (-) 631 Protein_1591 NAD(P)-dependent oxidoreductase -
  R8586_RS08050 - 1541298..1541498 (+) 201 WP_001834370.1 hypothetical protein -
  R8586_RS08055 (PC0038_16110) - 1541929..1542069 (+) 141 WP_000422775.1 MazG-like protein -
  R8586_RS08060 - 1542076..1542252 (+) 177 Protein_1594 MazG-like protein -
  R8586_RS08065 (PC0038_16120) thrS 1542310..1544253 (+) 1944 WP_000608331.1 threonine--tRNA ligase -
  R8586_RS08070 (PC0038_16130) - 1544302..1545276 (-) 975 WP_000887949.1 HAMP domain-containing histidine kinase -
  R8586_RS08075 (PC0038_16140) braR 1545269..1545946 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  R8586_RS08080 (PC0038_16150) - 1546102..1547175 (+) 1074 WP_001273833.1 DUF2974 domain-containing protein -
  R8586_RS08085 (PC0038_16160) - 1547266..1547568 (-) 303 WP_000281608.1 hypothetical protein -
  R8586_RS08090 (PC0038_16170) - 1547636..1548073 (-) 438 WP_001166792.1 Rrf2 family transcriptional regulator -
  R8586_RS08095 (PC0038_16180) - 1548149..1548991 (-) 843 WP_000160958.1 metallophosphoesterase -
  R8586_RS08100 (PC0038_16190) - 1549103..1549753 (+) 651 WP_000188497.1 metal-dependent transcriptional regulator -
  R8586_RS08105 (PC0038_16200) - 1550077..1550626 (+) 550 Protein_1603 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=82329 R8586_RS08075 WP_000548959.1 1545269..1545946(-) (braR) [Streptococcus pneumoniae strain PZ900700038]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=82329 R8586_RS08075 WP_000548959.1 1545269..1545946(-) (braR) [Streptococcus pneumoniae strain PZ900700038]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment