Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   NRK31_RS00460 Genome accession   NZ_CP123852
Coordinates   84573..85202 (+) Length   209 a.a.
NCBI ID   WP_000153535.1    Uniprot ID   W8TS97
Organism   Staphylococcus aureus strain 5812R     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 79573..90202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NRK31_RS00435 - 80005..80991 (-) 987 WP_042727578.1 aromatic acid exporter family protein -
  NRK31_RS00440 map 81466..82224 (+) 759 WP_000636144.1 type I methionyl aminopeptidase -
  NRK31_RS00445 - 82441..82827 (+) 387 WP_001110179.1 hypothetical protein -
  NRK31_RS00450 liaF 82842..83543 (+) 702 WP_259226284.1 cell wall-active antibiotics response protein LiaF -
  NRK31_RS00455 vraS 83540..84583 (+) 1044 WP_001017131.1 sensor histidine kinase Regulator
  NRK31_RS00460 vraR 84573..85202 (+) 630 WP_000153535.1 two-component system response regulator VraR Regulator
  NRK31_RS00465 - 85314..86531 (-) 1218 WP_042727579.1 YihY/virulence factor BrkB family protein -
  NRK31_RS00470 - 86809..87084 (-) 276 WP_000428172.1 YtxH domain-containing protein -
  NRK31_RS00475 - 87091..87555 (-) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  NRK31_RS00480 - 87702..87902 (+) 201 WP_000180463.1 DUF1128 family protein -
  NRK31_RS00485 - 87905..89161 (+) 1257 WP_001793428.1 aminopeptidase -
  NRK31_RS00490 - 89250..89780 (+) 531 WP_000184383.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23559.32 Da        Isoelectric Point: 5.3935

>NTDB_id=822737 NRK31_RS00460 WP_000153535.1 84573..85202(+) (vraR) [Staphylococcus aureus strain 5812R]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAHELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=822737 NRK31_RS00460 WP_000153535.1 84573..85202(+) (vraR) [Staphylococcus aureus strain 5812R]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAGGAAGCAATTGCCAAAGCCCATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB W8TS97

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

100

100

1
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373