Detailed information NTG0822722

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: R6U80_RS12330
• Genome accession: NZ_CP137623
• Coordinates: 2481581..2483551 (-)
• Length: 656 a.a.
• NCBI ID: WP_058223262.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain NCK401
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2476581..2488551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R6U80_RS12310 (R6U80_12310)	-	2476965..2478149 (-)	1185	WP_098397372.1	ABC transporter permease	-
R6U80_RS12315 (R6U80_12315)	-	2478726..2479610 (-)	885	WP_012898698.1	XRE/MutR family transcriptional regulator	-
R6U80_RS12320 (R6U80_12320)	ruvB	2479747..2480748 (-)	1002	WP_313791883.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
R6U80_RS12325 (R6U80_12325)	ruvA	2480875..2481468 (-)	594	WP_003131995.1	Holliday junction branch migration protein RuvA	Machinery gene
R6U80_RS12330 (R6U80_12330)	hexB	2481581..2483551 (-)	1971	WP_058223262.1	DNA mismatch repair endonuclease MutL	Machinery gene
R6U80_RS12335 (R6U80_12335)	-	2483681..2484376 (-)	696	WP_010906384.1	hypothetical protein	-
R6U80_RS12340 (R6U80_12340)	hexA	2484491..2487013 (-)	2523	WP_012898701.1	DNA mismatch repair protein MutS	Machinery gene
R6U80_RS12345 (R6U80_12345)	-	2487207..2487554 (-)	348	WP_058221293.1	RicAFT regulatory complex protein RicA family protein	-

Sequence

Protein

• Length: 656 a.a.
• Molecular weight: 73760.95 Da
• Isoelectric Point: 5.1824

>NTDB_id=822722 R6U80_RS12330 WP_058223262.1 2481581..2483551(-) (hexB) [Lactococcus lactis strain NCK401]
MGKIIELNEALANQIAAGEVVERPASVVKELVENSIDAGSSKIIINVEEAGLRLIEVIDNGLGLEKEDVALALRRHATSK
IKDSADLFRIRTLGFRGEALPSIASVSQMTIETSTAEEESGTKLIAKGGNIETLEPLAKRVGTKISVANLFYNTPARLKY
IKSLQAELSHITDIINRLSLAHPEISFTLVNEGKEFLKTAGNGDLRQVIAAIYGIGTAKKMRQIKGSDLDFELTGYVSIP
ELTRANRNYITILINGRFIKNFLLNRAILEGYGNRLMVGRFPFAILSIKIDPTLADVNVHPTKQEVRLSKERELMALISK
AIDEALSEGVLIPEALENLQGRAKEKESLSVQTELPLQNNPLYYDNVRQDFYVREEATFKINKNQPSNDSSEQTFDNFTE
NQLNTDAVNEKITDRTVESTTEITDNSLENTVSNFEIDFDNEAKISQSSTFPQLEYLAQLHATYLLCQSKEGLYLVDQHA
AQERIKYEYWKDKIGEVSMEQQILLAPYLFTLAKNDFIVLAEKKDLLHEAGVFLEEYGENQFILREHPIWLKETEIEKSI
NEMIDIILSSKEFSLKKYRHDLAAMVACKSSIKANHPLDAESARALLAELATCKNPYSCAHGRPTIVHFSGDDIQKMFRR
IQETHRSKAASWKDFE

Nucleotide

• Length: 1971 bp

>NTDB_id=822722 R6U80_RS12330 WP_058223262.1 2481581..2483551(-) (hexB) [Lactococcus lactis strain NCK401]
GTGGGAAAAATTATTGAACTAAATGAAGCGCTCGCCAATCAAATTGCTGCTGGAGAGGTGGTTGAGCGGCCTGCTAGTGT
TGTCAAAGAATTAGTCGAAAACTCAATTGATGCTGGAAGCAGTAAAATTATTATCAATGTTGAAGAAGCTGGTTTGCGAT
TAATTGAAGTCATTGATAATGGTTTGGGTTTGGAAAAAGAAGATGTGGCTTTGGCTTTACGTCGTCATGCAACAAGTAAA
ATCAAGGATTCGGCAGATTTGTTTCGGATTAGAACACTTGGTTTTCGGGGGGAGGCTCTGCCATCAATCGCTTCTGTCAG
CCAGATGACCATTGAAACAAGTACGGCTGAGGAAGAATCAGGAACAAAACTAATTGCTAAAGGTGGAAATATCGAAACTT
TAGAACCACTTGCTAAGCGCGTGGGGACGAAAATTTCTGTTGCTAATCTTTTTTATAATACACCAGCAAGACTCAAGTAT
ATCAAGTCCTTGCAGGCTGAACTTTCTCATATCACAGACATCATCAACCGATTGAGTCTGGCTCATCCAGAGATTTCCTT
TACTTTAGTTAATGAGGGTAAAGAATTTTTGAAAACGGCTGGAAATGGTGATTTACGTCAGGTTATTGCTGCAATTTATG
GCATAGGGACAGCGAAAAAAATGCGTCAAATCAAGGGTTCAGACTTAGATTTTGAACTAACAGGTTATGTCAGCATACCA
GAGCTGACAAGGGCTAATCGTAATTATATTACGATTTTAATAAATGGGCGATTTATCAAAAACTTTTTATTGAATCGGGC
AATTTTAGAAGGATATGGCAATCGATTGATGGTGGGACGGTTCCCTTTTGCTATTTTATCGATTAAAATTGACCCAACAC
TTGCTGATGTTAATGTTCATCCGACAAAACAAGAGGTGCGTTTGTCTAAAGAGCGTGAATTGATGGCTTTAATTTCTAAA
GCAATTGATGAGGCTTTATCAGAAGGTGTTTTGATTCCAGAAGCTTTGGAAAATTTGCAAGGAAGAGCTAAAGAAAAGGA
GAGTCTTTCTGTTCAAACGGAACTTCCTTTGCAAAATAATCCTTTATATTATGATAATGTTCGCCAAGATTTTTATGTCA
GAGAAGAGGCAACTTTTAAAATCAATAAAAATCAGCCTTCAAATGATTCGTCTGAACAAACTTTTGATAATTTTACAGAA
AATCAACTTAATACAGATGCTGTCAATGAAAAAATTACTGACAGAACTGTTGAAAGTACAACTGAAATTACTGACAACAG
TCTAGAAAATACTGTCAGCAACTTTGAAATTGATTTTGATAATGAAGCAAAGATAAGTCAGTCATCAACTTTTCCGCAGC
TTGAATACTTGGCACAATTGCATGCGACTTATTTACTTTGTCAGTCCAAAGAAGGACTTTATTTGGTTGACCAACATGCG
GCTCAAGAGCGAATAAAATATGAGTATTGGAAAGATAAAATTGGTGAGGTCAGTATGGAGCAACAAATTTTACTTGCACC
ATATTTGTTCACTTTAGCCAAAAATGATTTTATTGTTTTAGCCGAGAAGAAAGATTTGTTGCATGAAGCCGGTGTTTTCT
TAGAAGAATACGGAGAAAATCAATTCATTTTAAGAGAACATCCAATCTGGTTAAAAGAAACCGAGATAGAGAAATCAATT
AATGAAATGATTGATATTATTCTCTCATCAAAAGAATTTTCACTCAAAAAATATCGTCATGATTTAGCTGCAATGGTTGC
TTGCAAAAGTTCAATTAAAGCTAATCATCCCCTTGATGCCGAATCAGCTAGAGCATTGCTTGCAGAATTAGCAACTTGTA
AAAATCCTTATAGTTGTGCGCATGGACGGCCAACGATTGTTCATTTTTCAGGGGATGACATTCAAAAAATGTTCCGGAGA
ATCCAAGAAACGCATCGTTCAAAAGCAGCTTCGTGGAAAGATTTTGAGTAA

Domains

Predicted by InterProScan.

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-326)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-124)

• MutL C terminal dimerisation domain (MutL_C) (455-598)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	56.836	99.238	0.564