Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   R6U80_RS05970 Genome accession   NZ_CP137623
Coordinates   1209029..1210264 (+) Length   411 a.a.
NCBI ID   WP_012897750.1    Uniprot ID   -
Organism   Lactococcus lactis strain NCK401     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1204029..1215264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R6U80_RS05945 (R6U80_05945) - 1204864..1205457 (+) 594 WP_003132093.1 xanthine phosphoribosyltransferase -
  R6U80_RS05950 (R6U80_05950) - 1205506..1206810 (+) 1305 WP_033899494.1 nucleobase:cation symporter-2 family protein -
  R6U80_RS05955 (R6U80_05955) - 1206838..1207125 (-) 288 WP_233610933.1 hypothetical protein -
  R6U80_RS05960 (R6U80_05960) - 1207371..1207880 (-) 510 WP_010905785.1 tRNA (cytidine(34)-2'-O)-methyltransferase -
  R6U80_RS05965 (R6U80_05965) - 1208279..1208785 (+) 507 WP_010905786.1 dihydrofolate reductase -
  R6U80_RS05970 (R6U80_05970) clpX 1209029..1210264 (+) 1236 WP_012897750.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  R6U80_RS05975 (R6U80_05975) yihA 1210261..1210848 (+) 588 WP_313792055.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  R6U80_RS05980 (R6U80_05980) folB 1210902..1211252 (+) 351 WP_003132106.1 dihydroneopterin aldolase -
  R6U80_RS05985 (R6U80_05985) folE 1211332..1212381 (+) 1050 WP_012897751.1 GTP cyclohydrolase I FolE -
  R6U80_RS05990 (R6U80_05990) folP 1212378..1213451 (+) 1074 WP_313792054.1 dihydropteroate synthase -
  R6U80_RS05995 (R6U80_05995) - 1213454..1213951 (+) 498 WP_058223036.1 NUDIX domain-containing protein -
  R6U80_RS06000 (R6U80_06000) - 1213970..1215253 (+) 1284 WP_017864445.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -

Sequence

Protein


Download         Length: 411 a.a.        Molecular weight: 46024.89 Da        Isoelectric Point: 4.6053

>NTDB_id=822665 R6U80_RS05970 WP_012897750.1 1209029..1210264(+) (clpX) [Lactococcus lactis strain NCK401]
MSNTQNPNIHCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELREEQDSEMLEVKTPKEMFDHLNEYVIGQEKAK
RALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILL
KLLQASDFNIERAERGIIYIDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNI
LFIVGGAFDGIEEIVKQRLGEKIIGFGANNKKLNDDDSYMQEIIAEDIQKFGLIPEFIGRLPIVAALERLTEEDLIQILT
EPKNALIKQYKQLLLFDNVELEFEDEALMAIARKAIERKTGARGLRSIIEEVMMDIMFEVPSHEEITKVIINEAVVDGKA
EPQMIREAKKK

Nucleotide


Download         Length: 1236 bp        

>NTDB_id=822665 R6U80_RS05970 WP_012897750.1 1209029..1210264(+) (clpX) [Lactococcus lactis strain NCK401]
ATGTCAAATACACAAAATCCAAATATACATTGTTCTTTCTGCGGAAAGAGTCAAGATGATGTAAAAAAAATGATTGCCGG
TTCAGACGTTTATATTTGTAATGAATGTATTGAACTTTCAACTCGAATCTTAGAAGAAGAATTAAGAGAAGAACAAGATT
CAGAAATGCTTGAAGTTAAAACACCTAAAGAAATGTTTGACCATTTAAATGAATATGTGATAGGTCAAGAAAAAGCAAAA
CGTGCACTTGCAGTTGCCGTTTATAATCATTACAAACGAATTAATTTTACAGCAAGTAAAATTGCTGAAGATATTGAACT
ACAAAAATCAAATATTCTATTAATCGGACCTACCGGTTCTGGTAAGACTTTTCTCGCTCAAACTTTAGCGAAATCACTCA
ATGTTCCGTTTGCGATTGCAGATGCGACAAGTTTAACTGAAGCTGGTTATGTTGGAGAAGACGTTGAAAATATTCTCTTA
AAACTTTTACAAGCGAGTGATTTCAATATTGAACGTGCTGAACGTGGAATTATCTATATCGATGAAATTGATAAAATTGC
TAAAAAATCTGAAAATGTATCAATTACTCGTGACGTTTCCGGGGAAGGTGTTCAACAAGCCCTTTTGAAAATTATTGAAG
GGACAGTAGCTAGCGTTCCACCACAAGGTGGCCGTAAACATCCTAATCAAGAAATGATTCAAATTGATACCAAAAATATC
TTATTTATCGTTGGTGGAGCTTTTGACGGGATTGAAGAAATTGTCAAACAACGTTTAGGTGAAAAAATTATTGGTTTTGG
TGCCAATAATAAAAAATTAAATGACGATGACTCTTATATGCAAGAAATTATTGCCGAGGACATTCAAAAATTTGGATTAA
TCCCTGAATTTATTGGTCGTCTGCCAATTGTTGCTGCTTTGGAACGTCTGACCGAAGAGGATTTGATTCAAATTTTGACA
GAACCTAAAAATGCTTTGATTAAACAATATAAACAACTCCTTTTATTTGATAATGTTGAACTTGAATTTGAAGATGAAGC
CCTCATGGCAATTGCTAGAAAAGCAATTGAGCGCAAAACAGGAGCGCGTGGACTTCGTTCAATTATTGAGGAAGTAATGA
TGGATATCATGTTTGAAGTTCCAAGTCATGAAGAAATTACAAAAGTTATTATTAATGAAGCAGTTGTTGACGGAAAAGCT
GAGCCACAAATGATTCGAGAGGCCAAGAAAAAATGA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(108-304)

ClpX C4-type zinc finger (zf-C4_ClpX)

(10-46)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(310-388)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

76.808

97.567

0.749
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.883

95.864

0.564