Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX45_RS05775 Genome accession   NZ_CP123747
Coordinates   1129822..1130508 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.4     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1124822..1135508
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX45_RS05740 yqeH 1125349..1126449 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  QFX45_RS05745 aroE 1126463..1127269 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX45_RS05750 yhbY 1127273..1127563 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX45_RS05755 nadD 1127566..1128135 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX45_RS05760 yqeK 1128125..1128709 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX45_RS05765 rsfS 1128710..1129063 (+) 354 WP_001088022.1 ribosome silencing factor -
  QFX45_RS05770 - 1129066..1129782 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX45_RS05775 comEA 1129822..1130508 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX45_RS05780 - 1130600..1131061 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QFX45_RS05785 comEC 1131066..1133267 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX45_RS05790 holA 1133324..1134298 (+) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX45_RS05795 rpsT 1134343..1134594 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=822334 QFX45_RS05775 WP_001792568.1 1129822..1130508(+) (comEA) [Staphylococcus aureus strain 1.4]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822334 QFX45_RS05775 WP_001792568.1 1129822..1130508(+) (comEA) [Staphylococcus aureus strain 1.4]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969