Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   R2B38_RS23360 Genome accession   NZ_CP137549
Coordinates   5209109..5210167 (-) Length   352 a.a.
NCBI ID   WP_318021770.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5204109..5215167
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS23335 (R2B38_23335) cseB 5204297..5205004 (-) 708 WP_033286107.1 two-component system response regulator CseB -
  R2B38_RS23340 (R2B38_23340) - 5205191..5205880 (-) 690 WP_411978486.1 hypothetical protein -
  R2B38_RS23345 (R2B38_23345) - 5205868..5206407 (-) 540 WP_019064956.1 SigE family RNA polymerase sigma factor -
  R2B38_RS23350 (R2B38_23350) - 5206749..5207678 (-) 930 WP_318017993.1 A/G-specific adenine glycosylase -
  R2B38_RS23355 (R2B38_23355) - 5208235..5209080 (+) 846 WP_318017994.1 hypothetical protein -
  R2B38_RS23360 (R2B38_23360) disA 5209109..5210167 (-) 1059 WP_318021770.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  R2B38_RS23365 (R2B38_23365) radA/sms 5210305..5211714 (-) 1410 WP_318017995.1 DNA repair protein RadA Machinery gene
  R2B38_RS23370 (R2B38_23370) - 5211913..5213610 (+) 1698 WP_318017996.1 BACON domain-containing protein -
  R2B38_RS23375 (R2B38_23375) - 5213615..5214481 (-) 867 WP_318017997.1 hypothetical protein -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38035.70 Da        Isoelectric Point: 4.9024

>NTDB_id=822266 R2B38_RS23360 WP_318021770.1 5209109..5210167(-) (disA) [Streptomyces sp. N50]
MRASLSAVAPGTALRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFILDVEFTATRLRELCKLDGGIVVSSDLSKILRAG
VQLVPDPNIPTEETGTRHRTADRVSKQVAYPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVVQRLEMVRLIATEIAEYVVELGTDGRLLALQLEELIAGVEPERELVVRDYVPEPTAKRS
RTVTEALAELDALSHAELLELPTVARALGYTGSPEALDSAVSPRGFRLLAKVPRLPGAIIDRLVEHFGGLQKLLAASVDD
LQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=822266 R2B38_RS23360 WP_318021770.1 5209109..5210167(-) (disA) [Streptomyces sp. N50]
ATGCGCGCCTCACTGAGCGCCGTTGCCCCCGGCACGGCCCTGCGCGACGGCCTGGAACGCATCCTCCGCGGCAACACGGG
CGGCCTCATCGTGCTCGGCTCCGACAAGACCGTAGAAGCGATGTGCACAGGCGGTTTCATCCTGGACGTCGAGTTCACGG
CCACGCGCCTACGGGAACTCTGCAAACTGGACGGCGGCATCGTAGTGTCGTCCGACCTCTCGAAGATCCTCCGAGCGGGC
GTCCAACTGGTCCCGGACCCCAACATCCCCACCGAAGAGACAGGCACCCGCCACCGCACGGCGGACCGGGTCAGCAAGCA
GGTCGCCTACCCGGTGGTCTCCGTCTCCCAGTCCATGCGCCTGATCGCCCTCTACGTAGACGGCCAACGCCGCGTACTGG
AGGACTCGGCGGCAATCCTGTCCCGAGCCAACCAGGCCCTCGCCACCCTGGAGCGCTACAAGCTCCGCCTGGACGAGGTG
GCGGGAACGCTCTCGGCCCTGGAGATCGAGGACCTGGTGACGGTCCGAGACGTATCGGCAGTGGTCCAACGCCTTGAAAT
GGTCCGCCTGATCGCGACCGAGATCGCCGAATACGTCGTAGAGCTCGGCACGGACGGCCGCCTACTCGCCCTCCAGCTGG
AGGAGTTGATCGCAGGCGTGGAGCCGGAACGCGAACTGGTAGTACGCGACTACGTCCCCGAGCCCACGGCCAAACGCTCC
CGCACGGTGACCGAAGCCCTGGCCGAACTGGACGCCCTCTCCCACGCGGAACTCCTCGAACTCCCCACCGTGGCCCGCGC
GTTGGGCTACACCGGCTCCCCCGAGGCCCTCGACTCGGCGGTCTCCCCCCGAGGCTTCCGCCTCCTGGCCAAGGTCCCGC
GCCTCCCCGGCGCGATCATCGACCGCCTGGTGGAACACTTCGGCGGCCTCCAGAAACTCCTGGCAGCCAGCGTCGACGAC
CTCCAGACAGTGGACGGCGTAGGCGAGGCAAGGGCACGCAGCGTCCGTGAGGGCCTCTCCCGCCTGGCGGAGTCCTCGAT
CCTGGAACGCTACGTATAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(302-337)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.665

98.295

0.449