Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX58_RS06135 Genome accession   NZ_CP123745
Coordinates   1173625..1174311 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.7     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1168625..1179311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX58_RS06100 yqeH 1169152..1170252 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  QFX58_RS06105 aroE 1170266..1171072 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX58_RS06110 yhbY 1171076..1171366 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX58_RS06115 nadD 1171369..1171938 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX58_RS06120 yqeK 1171928..1172512 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX58_RS06125 rsfS 1172513..1172866 (+) 354 WP_001088022.1 ribosome silencing factor -
  QFX58_RS06130 - 1172869..1173585 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX58_RS06135 comEA 1173625..1174311 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX58_RS06140 - 1174403..1174864 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QFX58_RS06145 comEC 1174869..1177070 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX58_RS06150 holA 1177127..1178101 (+) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX58_RS06155 rpsT 1178146..1178397 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=822254 QFX58_RS06135 WP_001792568.1 1173625..1174311(+) (comEA) [Staphylococcus aureus strain 1.7]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822254 QFX58_RS06135 WP_001792568.1 1173625..1174311(+) (comEA) [Staphylococcus aureus strain 1.7]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969