Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R2B38_RS07215 Genome accession   NZ_CP137549
Coordinates   1697254..1697886 (-) Length   210 a.a.
NCBI ID   WP_318015466.1    Uniprot ID   -
Organism   Streptomyces sp. N50     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1692254..1702886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R2B38_RS07185 (R2B38_07185) - 1692659..1693624 (-) 966 WP_318015463.1 SPFH domain-containing protein -
  R2B38_RS07190 (R2B38_07190) - 1693799..1694233 (-) 435 WP_318015464.1 NfeD family protein -
  R2B38_RS07195 (R2B38_07195) - 1694310..1695101 (-) 792 WP_033286427.1 ABC transporter ATP-binding protein -
  R2B38_RS07200 (R2B38_07200) - 1695234..1696022 (+) 789 WP_318015465.1 hypothetical protein -
  R2B38_RS07205 (R2B38_07205) - 1696386..1696625 (-) 240 WP_033286425.1 chaplin family protein -
  R2B38_RS07210 (R2B38_07210) - 1696848..1697087 (-) 240 WP_033286424.1 chaplin -
  R2B38_RS07215 (R2B38_07215) vraR 1697254..1697886 (-) 633 WP_318015466.1 response regulator transcription factor Regulator
  R2B38_RS07220 (R2B38_07220) - 1697879..1699024 (-) 1146 WP_318015467.1 GAF domain-containing sensor histidine kinase -
  R2B38_RS07225 (R2B38_07225) - 1699210..1699905 (+) 696 WP_318015468.1 SDR family NAD(P)-dependent oxidoreductase -
  R2B38_RS07230 (R2B38_07230) - 1699902..1700342 (+) 441 Protein_1431 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  R2B38_RS51270 - 1700586..1701638 (+) 1053 WP_411978561.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  R2B38_RS07240 (R2B38_07240) - 1701937..1702701 (+) 765 WP_318015469.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 22753.09 Da        Isoelectric Point: 5.3618

>NTDB_id=822235 R2B38_RS07215 WP_318015466.1 1697254..1697886(-) (vraR) [Streptomyces sp. N50]
MADAIKVLIVDDHQVVRRGLRTFLEVQDDIEVVGEAADGAEGVARTEELKPDVVLMDVKMPGMDGIDALRRLRELDHPAR
VLIVTSFTEQRTVIPALRAGAAGYVYKDVDPDALAGAIRSVHAGHILLQPEVAGVLLSQEESNSGQGRGGSLTEREREVL
GLIADGREIARALVLSEKTVKTHVSNILMKLDLADRTQAALFAVRHGLTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=822235 R2B38_RS07215 WP_318015466.1 1697254..1697886(-) (vraR) [Streptomyces sp. N50]
GTGGCTGACGCAATCAAGGTGCTCATCGTCGACGACCACCAGGTCGTCCGCCGGGGCCTGCGCACCTTCCTGGAGGTGCA
GGACGACATCGAGGTCGTCGGCGAGGCGGCCGACGGCGCCGAAGGAGTCGCCCGCACCGAGGAGTTGAAGCCCGACGTCG
TCCTCATGGACGTCAAGATGCCGGGCATGGACGGCATCGACGCGCTGCGCAGACTCCGCGAACTCGACCACCCCGCGCGC
GTGTTGATCGTCACCAGCTTCACCGAACAGCGCACGGTGATCCCGGCCCTGCGCGCGGGCGCCGCCGGTTACGTCTACAA
GGACGTGGACCCGGACGCCCTGGCCGGCGCCATCCGTTCCGTCCACGCGGGCCACATCCTGCTCCAACCCGAGGTCGCCG
GCGTCCTGTTGTCCCAGGAGGAGTCCAACTCGGGGCAGGGGAGAGGCGGTTCGCTCACGGAGCGGGAGCGCGAGGTGCTC
GGCCTGATCGCCGACGGCCGCGAGATAGCCCGCGCCCTGGTGCTCTCCGAGAAGACGGTCAAGACCCACGTGTCGAACAT
CCTGATGAAGCTCGACCTGGCGGACCGCACGCAGGCGGCCCTGTTCGCCGTACGGCACGGTCTGACCAGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(151-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

45.327

100

0.462
  degU Bacillus subtilis subsp. subtilis str. 168

37.387

100

0.395