Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX62_RS05780 Genome accession   NZ_CP123744
Coordinates   1129672..1130358 (+) Length   228 a.a.
NCBI ID   WP_001792568.1    Uniprot ID   A0A133PXY3
Organism   Staphylococcus aureus strain 1.8     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1124672..1135358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX62_RS05745 yqeH 1125199..1126299 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  QFX62_RS05750 aroE 1126313..1127119 (+) 807 WP_000666761.1 shikimate dehydrogenase -
  QFX62_RS05755 yhbY 1127123..1127413 (+) 291 WP_000955231.1 ribosome assembly RNA-binding protein YhbY -
  QFX62_RS05760 nadD 1127416..1127985 (+) 570 WP_000725162.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX62_RS05765 yqeK 1127975..1128559 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX62_RS05770 rsfS 1128560..1128913 (+) 354 WP_001088022.1 ribosome silencing factor -
  QFX62_RS05775 - 1128916..1129632 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX62_RS05780 comEA 1129672..1130358 (+) 687 WP_001792568.1 ComEA family DNA-binding protein Machinery gene
  QFX62_RS05785 - 1130450..1130911 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QFX62_RS05790 comEC 1130916..1133117 (+) 2202 WP_001566051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX62_RS05795 holA 1133174..1134148 (+) 975 WP_304984666.1 DNA polymerase III subunit delta -
  QFX62_RS05800 rpsT 1134193..1134444 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25863.49 Da        Isoelectric Point: 9.3305

>NTDB_id=822214 QFX62_RS05780 WP_001792568.1 1129672..1130358(+) (comEA) [Staphylococcus aureus strain 1.8]
MVLLYQFLLRYKDFLTQWKLYILSAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHEKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822214 QFX62_RS05780 WP_001792568.1 1129672..1130358(+) (comEA) [Staphylococcus aureus strain 1.8]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTCTAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGAAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTTGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A133PXY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

98.238

99.561

0.978
  comEA Staphylococcus aureus N315

97.357

99.561

0.969