Detailed information NTG0822181

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: R5Y33_RS05025
• Genome accession: NZ_CP137531
• Coordinates: 976625..977869 (-)
• Length: 414 a.a.
• NCBI ID: WP_002220823.1
• Uniprot ID: A1KUJ4
• Organism: Neisseria meningitidis strain EXNM741
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 971625..982869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R5Y33_RS05005	-	971753..973141 (+)	1389	WP_002220827.1	DEAD/DEAH box helicase	-
R5Y33_RS05010	-	973783..974337 (-)	555	WP_002216993.1	hypothetical protein	-
R5Y33_RS05015	-	974422..974922 (-)	501	WP_002220826.1	hypothetical protein	-
R5Y33_RS05020	-	975326..976522 (+)	1197	WP_002220824.1	aspartate aminotransferase family protein	-
R5Y33_RS05025	clpX	976625..977869 (-)	1245	WP_002220823.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
R5Y33_RS05030	rbfA	978060..978431 (+)	372	WP_002220822.1	30S ribosome-binding factor RbfA	-
R5Y33_RS05035	truB	978464..979396 (+)	933	WP_002220819.1	tRNA pseudouridine(55) synthase TruB	-
R5Y33_RS05040	-	979687..980154 (+)	468	WP_025458714.1	site-specific DNA-methyltransferase	-
R5Y33_RS05045	-	980045..981865 (+)	1821	WP_079758563.1	site-specific DNA-methyltransferase	-

Sequence

Protein

• Length: 414 a.a.
• Molecular weight: 45079.49 Da
• Isoelectric Point: 4.9406

>NTDB_id=822181 R5Y33_RS05025 WP_002220823.1 976625..977869(-) (clpX) [Neisseria meningitidis strain EXNM741]
MSNENRTCSFCGKSKSHVKHLIEGENAFICDECVSNCIEILHEDGNDGTPSESAGGEPEESGKLPTPAEIVANLNDHVIG
QEQAKKALAVSVYNHYKRLRHPKAGANVELSKSNILLIGPTGSGKTLLAQSLARKLDVPFVMADATTLTEAGYVGEDVEQ
IITKLLGKCDFDVEKAQRGIVYIDEIDKISRKGDNPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPNQEFINVDT
TNILFICGGAFAGLEKVIRQRTEKGGIGFGASVHSKDENADITKLFGIVEPEDLIKFGLIPELIGRLPVIATLEELDEDA
LINILTEPKNALVKQYQALFGMENVELEFEEGALRSIARQAMERKTGARGLRSIVERCLLDTMYRLPDLKGLKKVVVGKA
VIEEGREPELVFEP

Nucleotide

• Length: 1245 bp

>NTDB_id=822181 R5Y33_RS05025 WP_002220823.1 976625..977869(-) (clpX) [Neisseria meningitidis strain EXNM741]
ATGTCCAACGAAAACCGTACCTGTTCCTTTTGCGGAAAATCCAAATCACACGTCAAACATTTAATTGAGGGCGAAAACGC
CTTTATCTGTGACGAATGCGTCTCAAACTGTATTGAAATATTGCATGAAGACGGAAATGACGGCACACCTTCGGAAAGTG
CCGGAGGGGAGCCGGAAGAATCCGGCAAGCTGCCCACGCCCGCCGAAATCGTCGCCAACCTCAACGACCACGTTATCGGT
CAGGAACAAGCCAAGAAAGCCTTGGCGGTGTCGGTGTACAACCATTACAAACGCCTGCGCCACCCGAAAGCCGGAGCTAA
TGTCGAATTGTCGAAATCCAACATCCTGCTTATCGGCCCGACCGGATCGGGTAAAACCCTGCTGGCGCAATCTTTGGCGC
GTAAACTGGACGTACCGTTCGTGATGGCGGATGCAACCACGCTGACTGAAGCAGGTTATGTCGGCGAAGATGTCGAGCAA
ATCATCACCAAACTGTTGGGCAAATGTGATTTCGATGTTGAAAAAGCCCAGCGCGGCATCGTCTATATCGACGAAATCGA
TAAAATTTCACGCAAAGGCGACAATCCGTCCATCACGCGCGACGTGTCCGGCGAAGGTGTGCAACAAGCCTTGCTGAAAC
TGATTGAAGGTACGGTGGCAAGTGTTCCGCCCCAAGGCGGCCGCAAGCATCCGAATCAGGAATTTATCAACGTCGATACC
ACCAACATCCTGTTTATCTGCGGCGGTGCGTTTGCAGGCTTGGAAAAAGTCATCCGCCAGCGCACCGAGAAAGGCGGTAT
CGGTTTCGGTGCGTCCGTTCACAGCAAGGACGAAAATGCCGACATTACCAAGCTGTTCGGCATCGTCGAACCGGAAGATT
TAATCAAATTCGGTCTGATTCCGGAATTAATCGGACGTTTGCCTGTGATTGCAACGTTAGAAGAACTGGATGAGGACGCG
CTGATTAATATTTTGACCGAGCCGAAAAATGCTTTGGTCAAGCAGTATCAAGCCTTGTTCGGTATGGAAAATGTCGAACT
GGAGTTTGAAGAAGGCGCATTGCGTTCCATCGCGCGTCAGGCAATGGAGCGCAAAACCGGCGCGCGCGGCCTGCGTTCCA
TCGTCGAACGCTGCCTGTTGGATACGATGTACCGCCTGCCCGATTTGAAAGGCTTGAAAAAAGTGGTGGTCGGTAAGGCA
GTCATCGAAGAGGGCAGGGAACCGGAATTGGTGTTCGAGCCCTGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (316-387)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

• ClpX C4-type zinc finger (zf-C4_ClpX) (7-43)

3D structure

• AlphaFold DB: A1KUJ4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	56.039	100	0.56
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	54.39	99.034	0.539