Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   QFX63_RS05740 Genome accession   NZ_CP123741
Coordinates   1195627..1196499 (+) Length   290 a.a.
NCBI ID   WP_000593192.1    Uniprot ID   A0A140HKN1
Organism   Staphylococcus aureus strain 2.2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1190627..1201499
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX63_RS05720 sucC 1190741..1191907 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  QFX63_RS05725 sucD 1191929..1192837 (+) 909 WP_000110251.1 succinate--CoA ligase subunit alpha -
  QFX63_RS05730 - 1193064..1194182 (+) 1119 WP_001041667.1 LysM peptidoglycan-binding domain-containing protein -
  QFX63_RS05735 fmhC 1194210..1195454 (+) 1245 WP_000672867.1 FemA/FemB family glycyltransferase FmhC -
  QFX63_RS05740 dprA 1195627..1196499 (+) 873 WP_000593192.1 DNA-processing protein DprA Machinery gene
  QFX63_RS05745 topA 1196673..1198748 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  QFX63_RS05750 trmFO 1198904..1200211 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33564.99 Da        Isoelectric Point: 9.5094

>NTDB_id=822091 QFX63_RS05740 WP_000593192.1 1195627..1196499(+) (dprA) [Staphylococcus aureus strain 2.2]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=822091 QFX63_RS05740 WP_000593192.1 1195627..1196499(+) (dprA) [Staphylococcus aureus strain 2.2]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A140HKN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

100

100

1
  dprA Staphylococcus aureus N315

99.655

100

0.997