Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX50_RS11350 Genome accession   NZ_CP123740
Coordinates   2329049..2329735 (-) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain 2.3b     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2324049..2334735
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX50_RS11330 rpsT 2324963..2325214 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  QFX50_RS11335 holA 2325259..2326233 (-) 975 WP_001282568.1 DNA polymerase III subunit delta -
  QFX50_RS11340 comEC 2326290..2328491 (-) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX50_RS11345 - 2328496..2328957 (-) 462 WP_000439693.1 ComE operon protein 2 -
  QFX50_RS11350 comEA 2329049..2329735 (-) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  QFX50_RS11355 - 2329775..2330491 (-) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX50_RS11360 rsfS 2330494..2330847 (-) 354 WP_001088022.1 ribosome silencing factor -
  QFX50_RS11365 yqeK 2330848..2331432 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX50_RS11370 nadD 2331422..2331991 (-) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX50_RS11375 yhbY 2331994..2332284 (-) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  QFX50_RS11380 aroE 2332288..2333094 (-) 807 WP_000666748.1 shikimate dehydrogenase -
  QFX50_RS11385 yqeH 2333108..2334208 (-) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=822069 QFX50_RS11350 WP_001793467.1 2329049..2329735(-) (comEA) [Staphylococcus aureus strain 2.3b]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822069 QFX50_RS11350 WP_001793467.1 2329049..2329735(-) (comEA) [Staphylococcus aureus strain 2.3b]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974