Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QFX46_RS06280 Genome accession   NZ_CP123739
Coordinates   1179250..1179936 (+) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain 2.5     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1174250..1184936
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QFX46_RS06245 yqeH 1174777..1175877 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  QFX46_RS06250 aroE 1175891..1176697 (+) 807 WP_000666748.1 shikimate dehydrogenase -
  QFX46_RS06255 yhbY 1176701..1176991 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  QFX46_RS06260 nadD 1176994..1177563 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QFX46_RS06265 yqeK 1177553..1178137 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QFX46_RS06270 rsfS 1178138..1178491 (+) 354 WP_001088022.1 ribosome silencing factor -
  QFX46_RS06275 - 1178494..1179210 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  QFX46_RS06280 comEA 1179250..1179936 (+) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  QFX46_RS06285 - 1180028..1180489 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QFX46_RS06290 comEC 1180494..1182695 (+) 2202 WP_001566670.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QFX46_RS06295 holA 1182752..1183726 (+) 975 WP_001282568.1 DNA polymerase III subunit delta -
  QFX46_RS06300 rpsT 1183771..1184022 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=822012 QFX46_RS06280 WP_001793467.1 1179250..1179936(+) (comEA) [Staphylococcus aureus strain 2.5]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=822012 QFX46_RS06280 WP_001793467.1 1179250..1179936(+) (comEA) [Staphylococcus aureus strain 2.5]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974