Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4705_RS07275 Genome accession   NZ_CP137115
Coordinates   1378441..1379073 (+) Length   210 a.a.
NCBI ID   WP_000698438.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20614-6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1373441..1384073
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS07250 mvaD 1373718..1374671 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  R4705_RS07255 - 1374658..1375665 (+) 1008 WP_000562427.1 phosphomevalonate kinase -
  R4705_RS07260 fni 1375649..1376659 (+) 1011 WP_000210616.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4705_RS07265 liaF 1376737..1377435 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R4705_RS07270 - 1377432..1378427 (+) 996 WP_000743662.1 sensor histidine kinase -
  R4705_RS07275 vraR 1378441..1379073 (+) 633 WP_000698438.1 response regulator transcription factor Regulator
  R4705_RS07280 - 1379149..1379843 (+) 695 Protein_1386 DNA alkylation repair protein -
  R4705_RS07285 - 1379993..1380232 (+) 240 WP_000754501.1 hypothetical protein -
  R4705_RS07290 cbpG 1380313..1380903 (+) 591 Protein_1388 choline-binding protein CbpG -
  R4705_RS07295 - 1381205..1381597 (+) 393 WP_000378125.1 tyrosine-type recombinase/integrase -
  R4705_RS07300 tig 1381758..1383041 (+) 1284 WP_000116468.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23583.06 Da        Isoelectric Point: 4.5791

>NTDB_id=820258 R4705_RS07275 WP_000698438.1 1378441..1379073(+) (vraR) [Streptococcus pneumoniae strain 20614-6]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQATVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=820258 R4705_RS07275 WP_000698438.1 1378441..1379073(+) (vraR) [Streptococcus pneumoniae strain 20614-6]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGACTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41