Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R4705_RS02335 Genome accession   NZ_CP137115
Coordinates   443778..444455 (-) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain 20614-6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 438778..449455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4705_RS02305 - 438953..439582 (-) 630 WP_000762090.1 NAD(P)-dependent oxidoreductase -
  R4705_RS02310 - 439818..440181 (+) 364 Protein_455 hypothetical protein -
  R4705_RS02315 - 440438..440578 (+) 141 WP_000422775.1 MazG-like protein -
  R4705_RS02320 - 440585..440761 (+) 177 WP_000166031.1 MazG-like protein -
  R4705_RS02325 thrS 440819..442762 (+) 1944 WP_000608337.1 threonine--tRNA ligase -
  R4705_RS02330 - 442811..443785 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  R4705_RS02335 braR 443778..444455 (-) 678 WP_000548959.1 response regulator transcription factor Regulator
  R4705_RS02340 - 444611..445684 (+) 1074 WP_001273813.1 DUF2974 domain-containing protein -
  R4705_RS02345 - 445775..446077 (-) 303 WP_000281595.1 hypothetical protein -
  R4705_RS02350 - 446146..446583 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R4705_RS02355 - 446659..447501 (-) 843 WP_000160933.1 metallophosphoesterase -
  R4705_RS02360 - 447613..448263 (+) 651 WP_000188504.1 metal-dependent transcriptional regulator -
  R4705_RS02365 - 448440..449117 (+) 678 WP_000260183.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=820192 R4705_RS02335 WP_000548959.1 443778..444455(-) (braR) [Streptococcus pneumoniae strain 20614-6]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=820192 R4705_RS02335 WP_000548959.1 443778..444455(-) (braR) [Streptococcus pneumoniae strain 20614-6]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369