Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R4701_RS08410 Genome accession   NZ_CP137114
Coordinates   1637597..1638274 (+) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain 15P3054     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1632597..1643274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS08380 - 1632932..1633669 (-) 738 WP_000749124.1 nicotinamide mononucleotide transporter -
  R4701_RS08385 - 1633789..1634439 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  R4701_RS08390 - 1634551..1635393 (+) 843 WP_000160943.1 metallophosphoesterase -
  R4701_RS08395 - 1635469..1635906 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R4701_RS08400 - 1635975..1636277 (+) 303 WP_000281601.1 hypothetical protein -
  R4701_RS08405 - 1636368..1637441 (-) 1074 WP_001273828.1 DUF2974 domain-containing protein -
  R4701_RS08410 braR 1637597..1638274 (+) 678 WP_000548991.1 response regulator transcription factor Regulator
  R4701_RS08415 - 1638267..1639241 (+) 975 WP_000887972.1 HAMP domain-containing histidine kinase -
  R4701_RS08420 thrS 1639290..1641233 (-) 1944 WP_000608330.1 threonine--tRNA ligase -
  R4701_RS08425 - 1641291..1641467 (-) 177 WP_000166031.1 MazG-like protein -
  R4701_RS08430 - 1641474..1641614 (-) 141 WP_000422775.1 MazG-like protein -
  R4701_RS08435 - 1642045..1642245 (-) 201 WP_001826938.1 hypothetical protein -
  R4701_RS08440 - 1642484..1643113 (+) 630 Protein_1620 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=820155 R4701_RS08410 WP_000548991.1 1637597..1638274(+) (braR) [Streptococcus pneumoniae strain 15P3054]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=820155 R4701_RS08410 WP_000548991.1 1637597..1638274(+) (braR) [Streptococcus pneumoniae strain 15P3054]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTTTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369