Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4701_RS03320 Genome accession   NZ_CP137114
Coordinates   661193..661825 (-) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15P3054     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 656193..666825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4701_RS03290 tig 657343..658626 (-) 1284 WP_000116472.1 trigger factor -
  R4701_RS03295 - 658787..659179 (-) 393 WP_000378121.1 tyrosine-type recombinase/integrase -
  R4701_RS03300 - 659481..660083 (-) 603 Protein_656 trypsin-like serine peptidase -
  R4701_RS03305 - 660542..660686 (-) 145 Protein_657 DNA alkylation repair protein -
  R4701_RS03310 - 660714..660968 (-) 255 WP_000729868.1 DNA alkylation repair protein -
  R4701_RS03315 - 660950..661192 (-) 243 WP_001820556.1 DNA alkylation repair protein -
  R4701_RS03320 vraR 661193..661825 (-) 633 WP_000698432.1 response regulator transcription factor Regulator
  R4701_RS03325 - 661839..662834 (-) 996 WP_000743661.1 sensor histidine kinase -
  R4701_RS03330 liaF 662831..663529 (-) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  R4701_RS03335 fni 663607..664617 (-) 1011 WP_000210623.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4701_RS03340 - 664601..665608 (-) 1008 WP_000562442.1 phosphomevalonate kinase -
  R4701_RS03345 mvaD 665595..666548 (-) 954 WP_000373457.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=820085 R4701_RS03320 WP_000698432.1 661193..661825(-) (vraR) [Streptococcus pneumoniae strain 15P3054]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=820085 R4701_RS03320 WP_000698432.1 661193..661825(-) (vraR) [Streptococcus pneumoniae strain 15P3054]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41