Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QAO40_RS10190 Genome accession   NZ_CP123166
Coordinates   2064025..2064654 (-) Length   209 a.a.
NCBI ID   WP_171505353.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BE-MSSA5     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2059025..2069654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO40_RS10160 (QAO40_10185) - 2059445..2059975 (-) 531 WP_000184383.1 acyl-CoA thioesterase -
  QAO40_RS10165 (QAO40_10190) - 2060065..2061321 (-) 1257 WP_001795108.1 aminopeptidase -
  QAO40_RS10170 (QAO40_10195) - 2061324..2061524 (-) 201 WP_000180460.1 DUF1128 family protein -
  QAO40_RS10175 (QAO40_10200) - 2061671..2062135 (+) 465 WP_000228666.1 low molecular weight protein-tyrosine-phosphatase -
  QAO40_RS10180 (QAO40_10205) - 2062142..2062417 (+) 276 WP_000428172.1 YtxH domain-containing protein -
  QAO40_RS10185 (QAO40_10210) - 2062695..2063912 (+) 1218 WP_000037075.1 YihY/virulence factor BrkB family protein -
  QAO40_RS10190 (QAO40_10215) vraR 2064025..2064654 (-) 630 WP_171505353.1 two-component system response regulator VraR Regulator
  QAO40_RS10195 (QAO40_10220) vraS 2064644..2065687 (-) 1044 WP_001017131.1 sensor histidine kinase Regulator
  QAO40_RS10200 (QAO40_10225) liaF 2065684..2066385 (-) 702 WP_000149064.1 cell wall-active antibiotics response protein LiaF -
  QAO40_RS10205 (QAO40_10230) - 2066400..2066786 (-) 387 WP_001110179.1 hypothetical protein -
  QAO40_RS10210 (QAO40_10235) map 2067003..2067761 (-) 759 WP_000636142.1 type I methionyl aminopeptidase -
  QAO40_RS10215 (QAO40_10240) - 2068292..2069278 (+) 987 WP_000999717.1 FUSC family protein -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23585.36 Da        Isoelectric Point: 5.1790

>NTDB_id=819882 QAO40_RS10190 WP_171505353.1 2064025..2064654(-) (vraR) [Staphylococcus aureus strain BE-MSSA5]
MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKAYELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVL
MLTSFIEDKEVYRALDAGVDSYILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=819882 QAO40_RS10190 WP_171505353.1 2064025..2064654(-) (vraR) [Staphylococcus aureus strain BE-MSSA5]
ATGACGATTAAAGTATTGTTTGTGGATGATCATGAAATGGTACGTATAGGAATTTCAAGTTATCTATCAACGCAAAGTGA
TATTGAAGTAGTTGGTGAAGGCGCTTCTGGTAAAGAAGCAATTGCCAAAGCCTATGAGTTGAAGCCAGATTTAATTTTAA
TGGATTTACTTATGGAAGACATGGATGGTGTAGAAGCGACGACTCAGATTAAAAAAGATTTACCGCAAATTAAAGTATTA
ATGTTAACTAGTTTTATTGAAGATAAAGAGGTATATCGTGCATTAGATGCAGGTGTCGATAGTTACATTTTAAAAACAAC
AAGTGCAAAAGATATCGCCGATGCAGTTCGTAAAACTTCTAGAGGAGAATCTGTTTTTGAACCGGAAGTTTTAGTGAAAA
TGCGTAACCGTATGAAAAAGCGCGCAGAGTTATATGAAATGCTTACAGAACGAGAAATGGAAATATTATTATTGATTGCG
AAAGGTTACTCAAATCAAGAAATTGCTAGTGCATCGCATATTACTATTAAAACGGTTAAGACACATGTGAGTAACATTTT
AAGTAAGTTAGAAGTGCAAGATAGAACACAAGCTGTCATCTATGCATTCCAACATAATTTAATTCAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

99.522

100

0.995
  degU Bacillus subtilis subsp. subtilis str. 168

34.821

100

0.373