Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8613_RS08065 Genome accession   NZ_AP026919
Coordinates   1549073..1549750 (-) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700012     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1544073..1554750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8613_RS08035 (PC0012_15730) - 1544235..1544864 (-) 630 WP_000762078.1 NAD(P)-dependent oxidoreductase -
  R8613_RS08040 - 1545103..1545303 (+) 201 WP_001814296.1 hypothetical protein -
  R8613_RS08045 (PC0012_15740) - 1545733..1545873 (+) 141 WP_000422775.1 MazG-like protein -
  R8613_RS08050 (PC0012_15750) - 1545880..1546056 (+) 177 WP_000166031.1 MazG-like protein -
  R8613_RS08055 (PC0012_15760) thrS 1546114..1548057 (+) 1944 WP_000608349.1 threonine--tRNA ligase -
  R8613_RS08060 (PC0012_15770) - 1548106..1549080 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  R8613_RS08065 (PC0012_15780) braR 1549073..1549750 (-) 678 WP_000548961.1 response regulator transcription factor Regulator
  R8613_RS08070 (PC0012_15790) - 1549906..1550979 (+) 1074 WP_001273814.1 DUF2974 domain-containing protein -
  R8613_RS08075 (PC0012_15800) - 1551070..1551372 (-) 303 WP_000281609.1 hypothetical protein -
  R8613_RS08080 (PC0012_15810) - 1551440..1551877 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R8613_RS08085 (PC0012_15820) - 1551953..1552795 (-) 843 WP_219565559.1 metallophosphoesterase -
  R8613_RS08090 (PC0012_15830) - 1552907..1553557 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  R8613_RS08095 (PC0012_15840) - 1553859..1554408 (+) 550 Protein_1609 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=81975 R8613_RS08065 WP_000548961.1 1549073..1549750(-) (braR) [Streptococcus pneumoniae strain PZ900700012]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=81975 R8613_RS08065 WP_000548961.1 1549073..1549750(-) (braR) [Streptococcus pneumoniae strain PZ900700012]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364

Multiple sequence alignment