Detailed information NTG0819457

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY80_RS10395
• Genome accession: NZ_CP123142
• Coordinates: 2065932..2066819 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain GE-MRSA21
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2060932..2071819

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY80_RS10365 (QAY80_10360)	-	2060951..2061043 (+)	93	WP_010956583.1	hypothetical protein	-
QAY80_RS10370 (QAY80_10365)	-	2061151..2061648 (-)	498	WP_001065268.1	glutathione peroxidase	-
QAY80_RS10375 (QAY80_10370)	-	2061658..2061918 (-)	261	WP_001791974.1	hypothetical protein	-
QAY80_RS10380 (QAY80_10375)	-	2062300..2062413 (-)	114	Protein_2016	hypothetical protein	-
QAY80_RS10385 (QAY80_10380)	-	2063072..2065072 (-)	2001	WP_411896872.1	FtsX-like permease family protein	-
QAY80_RS10390 (QAY80_10385)	-	2065069..2065824 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QAY80_RS10395 (QAY80_10390)	braS	2065932..2066819 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY80_RS10400 (QAY80_10395)	braR	2066830..2067495 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY80_RS10405 (QAY80_10400)	-	2067521..2067721 (-)	201	WP_000604730.1	hypothetical protein	-
QAY80_RS10410 (QAY80_10405)	-	2067919..2069343 (+)	1425	WP_000953755.1	alkaline phosphatase	-
QAY80_RS10415	-	2069403..2069504 (-)	102	WP_000731976.1	SE2200 family small protein	-
QAY80_RS10420 (QAY80_10415)	-	2069626..2070081 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY80_RS10425 (QAY80_10420)	-	2070326..2071087 (-)	762	WP_000323441.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=819457 QAY80_RS10395 WP_000143425.1 2065932..2066819(-) (braS) [Staphylococcus aureus strain GE-MRSA21]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=819457 QAY80_RS10395 WP_000143425.1 2065932..2066819(-) (braS) [Staphylococcus aureus strain GE-MRSA21]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1