Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | QAY82_RS09550 | Genome accession | NZ_CP123137 |
| Coordinates | 1960704..1962332 (+) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain GE-MRSA23 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1923827..1967553 | 1960704..1962332 | within | 0 |
| SCCmec | 1959333..1980673 | 1960704..1962332 | within | 0 |
Gene organization within MGE regions
Location: 1923827..1980673
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QAY82_RS09395 (QAY82_09400) | - | 1923827..1926980 (-) | 3154 | Protein_1812 | AAA domain-containing protein | - |
| QAY82_RS09400 (QAY82_09405) | - | 1927247..1927849 (-) | 603 | WP_000908956.1 | hypothetical protein | - |
| QAY82_RS09405 (QAY82_09410) | - | 1928057..1928353 (-) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| QAY82_RS09410 (QAY82_09415) | - | 1928402..1928605 (-) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| QAY82_RS09415 (QAY82_09420) | - | 1928914..1929900 (+) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| QAY82_RS09420 | - | 1930086..1930300 (+) | 215 | Protein_1817 | universal stress protein | - |
| QAY82_RS09425 (QAY82_09425) | sqr | 1930567..1931760 (-) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| QAY82_RS09430 (QAY82_09430) | cstB | 1931779..1933113 (-) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| QAY82_RS09435 (QAY82_09435) | cstA | 1933144..1934208 (-) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| QAY82_RS09440 (QAY82_09440) | cstR | 1934345..1934605 (+) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| QAY82_RS09445 (QAY82_09445) | - | 1934605..1935360 (+) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| QAY82_RS09450 (QAY82_09450) | - | 1935458..1935546 (+) | 89 | Protein_1823 | hypothetical protein | - |
| QAY82_RS09455 (QAY82_09455) | - | 1935851..1936206 (+) | 356 | Protein_1824 | tRNA-dihydrouridine synthase | - |
| QAY82_RS09460 (QAY82_09460) | - | 1936304..1938049 (-) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| QAY82_RS09465 (QAY82_09465) | - | 1938196..1938288 (-) | 93 | WP_001790000.1 | hypothetical protein | - |
| QAY82_RS09470 (QAY82_09470) | - | 1938252..1938386 (+) | 135 | WP_001790628.1 | hypothetical protein | - |
| QAY82_RS09475 (QAY82_09475) | - | 1938636..1940144 (-) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| QAY82_RS09480 (QAY82_09480) | - | 1940259..1940885 (+) | 627 | WP_001176969.1 | hypothetical protein | - |
| QAY82_RS09485 | cch1 | 1942004..1943779 (+) | 1776 | Protein_1830 | cassette chromosome replicative helicase | - |
| QAY82_RS09490 (QAY82_09495) | - | 1944324..1944881 (-) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| QAY82_RS09495 (QAY82_09500) | - | 1944897..1946918 (-) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| QAY82_RS09500 (QAY82_09505) | kdpA | 1946937..1948613 (-) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| QAY82_RS09505 | kdpF | 1948634..1948714 (-) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| QAY82_RS09510 (QAY82_09510) | - | 1948881..1951550 (+) | 2670 | WP_000446429.1 | sensor histidine kinase | - |
| QAY82_RS09515 (QAY82_09515) | - | 1951525..1952220 (+) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| QAY82_RS09520 (QAY82_09520) | - | 1952933..1953868 (+) | 936 | Protein_1837 | YfcC family protein | - |
| QAY82_RS09525 (QAY82_09525) | - | 1954379..1955520 (+) | 1142 | Protein_1838 | IS3-like element ISSau4 family transposase | - |
| QAY82_RS09530 (QAY82_09530) | - | 1955771..1956817 (+) | 1047 | WP_001060127.1 | hypothetical protein | - |
| QAY82_RS09535 (QAY82_09535) | ssb | 1957010..1957306 (+) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| QAY82_RS09540 (QAY82_09540) | cch1 | 1957306..1959099 (+) | 1794 | WP_000195105.1 | cassette chromosome replicative helicase | - |
| QAY82_RS09545 (QAY82_09545) | ccrA | 1959333..1960682 (+) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| QAY82_RS09550 (QAY82_09550) | ccrB | 1960704..1962332 (+) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| QAY82_RS09555 (QAY82_09555) | - | 1962850..1963200 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| QAY82_RS09560 (QAY82_09560) | - | 1963287..1963598 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| QAY82_RS09565 (QAY82_09565) | - | 1963616..1964122 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| QAY82_RS09570 (QAY82_09570) | - | 1964143..1964460 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| QAY82_RS09575 (QAY82_09575) | - | 1964579..1965664 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| QAY82_RS09580 (QAY82_09580) | - | 1965661..1967553 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| QAY82_RS09585 (QAY82_09585) | - | 1967560..1967937 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| QAY82_RS09590 (QAY82_09590) | - | 1968088..1968870 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| QAY82_RS09595 (QAY82_09595) | erm(A) | 1968996..1969727 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| QAY82_RS09600 | - | 1969785..1969844 (-) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| QAY82_RS09605 (QAY82_09600) | - | 1970236..1970898 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| QAY82_RS09610 (QAY82_09605) | - | 1971243..1971881 (-) | 639 | Protein_1855 | sulfite exporter TauE/SafE family protein | - |
| QAY82_RS09615 (QAY82_09610) | cstR | 1971881..1972141 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| QAY82_RS09620 (QAY82_09615) | - | 1972277..1973341 (+) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| QAY82_RS09625 (QAY82_09620) | cstB | 1973374..1974708 (+) | 1335 | Protein_1858 | persulfide dioxygenase-sulfurtransferase CstB | - |
| QAY82_RS09630 (QAY82_09625) | - | 1974822..1975931 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| QAY82_RS09635 (QAY82_09630) | psm-mec | 1976286..1976354 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| QAY82_RS09640 (QAY82_09635) | mecI | 1976439..1976810 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| QAY82_RS09645 (QAY82_09640) | mecR1 | 1976810..1978567 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| QAY82_RS09650 (QAY82_09645) | mecA | 1978664..1980673 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=819371 QAY82_RS09550 WP_001186602.1 1960704..1962332(+) (ccrB) [Staphylococcus aureus strain GE-MRSA23]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=819371 QAY82_RS09550 WP_001186602.1 1960704..1962332(+) (ccrB) [Staphylococcus aureus strain GE-MRSA23]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |