Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4715_RS03310 Genome accession   NZ_CP137108
Coordinates   687766..688398 (-) Length   210 a.a.
NCBI ID   WP_277772036.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain OXT     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 682766..693398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4715_RS03290 tig 683574..684857 (-) 1284 WP_317830151.1 trigger factor -
  R4715_RS03295 cbpC 685175..686194 (-) 1020 WP_000698044.1 choline-binding protein CbpC -
  R4715_RS11185 - 686212..687546 (-) 1335 WP_000750731.1 trypsin-like peptidase domain-containing protein -
  R4715_RS03310 vraR 687766..688398 (-) 633 WP_277772036.1 response regulator transcription factor Regulator
  R4715_RS03315 - 688412..689407 (-) 996 WP_277772037.1 sensor histidine kinase -
  R4715_RS03320 liaF 689404..690102 (-) 699 WP_317830152.1 cell wall-active antibiotics response protein LiaF -
  R4715_RS03325 fni 690179..691189 (-) 1011 WP_317830153.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4715_RS03330 - 691173..692180 (-) 1008 WP_000562413.1 phosphomevalonate kinase -
  R4715_RS03335 mvaD 692167..693120 (-) 954 WP_000373457.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23634.24 Da        Isoelectric Point: 5.0123

>NTDB_id=819368 R4715_RS03310 WP_277772036.1 687766..688398(-) (vraR) [Streptococcus pneumoniae strain OXT]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGSQGIDLSLKLRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEDLTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGREDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=819368 R4715_RS03310 WP_277772036.1 687766..688398(-) (vraR) [Streptococcus pneumoniae strain OXT]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCGGCAAACGGGTCTCAGGGGATTGACTTGTCCTTGAAATTGCGTCCAGATGTTATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGATGCGACCTTGGCTATCCTCAAAGAATGGCCTGAAGCCAAGATTTTAATTGTG
ACTTCTTACTTGGACAATGAAAAAATCATGCCAGTATTGAATGCTGGGGCTAAAGGTTATATGCTTAAGACTTCTAGTGC
AGATGAATTGCTCCATGCTGTCCGCAAGGTAGCTGCTGGGGAGTTAGCCATTGAGCAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGAAATCACATGGAACTTCATGAGGACCTAACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAT
GAAAATCAGCGCATCGCTGATGAACTTTTTATCTCTCTTAAGACGGTCAAGACCCATGTGTCCAATATCCTTGCTAAGCT
TGAGGTCAGTGATCGCACTCAGGCAGCAGTCTATGCCTTTCAGCACCACTTGGTGGGGCGGGAAGATTTTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.675

99.524

0.514
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405