Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R4711_RS08810 Genome accession   NZ_CP137107
Coordinates   1722021..1722698 (+) Length   225 a.a.
NCBI ID   WP_000548959.1    Uniprot ID   Q9S1K2
Organism   Streptococcus pneumoniae strain 15H4024     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1717021..1727698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS08785 - 1718212..1718862 (-) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  R4711_RS08790 - 1718974..1719816 (+) 843 WP_000160943.1 metallophosphoesterase -
  R4711_RS08795 - 1719892..1720329 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R4711_RS08800 - 1720398..1720701 (+) 304 Protein_1691 hypothetical protein -
  R4711_RS08805 - 1720792..1721865 (-) 1074 WP_001273828.1 DUF2974 domain-containing protein -
  R4711_RS08810 braR 1722021..1722698 (+) 678 WP_000548959.1 response regulator transcription factor Regulator
  R4711_RS08815 - 1722691..1723665 (+) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  R4711_RS08820 thrS 1723714..1725657 (-) 1944 WP_050263883.1 threonine--tRNA ligase -
  R4711_RS08825 - 1725715..1725890 (-) 176 Protein_1696 MazG-like protein -
  R4711_RS08830 - 1725897..1726037 (-) 141 WP_000422775.1 MazG-like protein -
  R4711_RS08835 - 1726468..1726668 (-) 201 WP_050263882.1 hypothetical protein -
  R4711_RS08840 - 1726907..1727536 (+) 630 WP_050115971.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25964.16 Da        Isoelectric Point: 5.1362

>NTDB_id=819322 R4711_RS08810 WP_000548959.1 1722021..1722698(+) (braR) [Streptococcus pneumoniae strain 15H4024]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=819322 R4711_RS08810 WP_000548959.1 1722021..1722698(+) (braR) [Streptococcus pneumoniae strain 15H4024]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1K2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369