Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R4702_RS08820 Genome accession   NZ_CP137106
Coordinates   1719353..1720030 (+) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae strain 16P4028     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1714353..1725030
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4702_RS08790 - 1714673..1715222 (-) 550 Protein_1696 nicotinamide mononucleotide transporter -
  R4702_RS08795 - 1715546..1716196 (-) 651 WP_000188497.1 metal-dependent transcriptional regulator -
  R4702_RS08800 - 1716308..1717150 (+) 843 WP_000160958.1 metallophosphoesterase -
  R4702_RS08805 - 1717226..1717663 (+) 438 WP_317809743.1 Rrf2 family transcriptional regulator -
  R4702_RS08810 - 1717731..1718033 (+) 303 WP_000281608.1 hypothetical protein -
  R4702_RS08815 - 1718124..1719197 (-) 1074 WP_001273834.1 DUF2974 domain-containing protein -
  R4702_RS08820 braR 1719353..1720030 (+) 678 WP_000548991.1 response regulator transcription factor Regulator
  R4702_RS08825 - 1720023..1720997 (+) 975 WP_000887972.1 HAMP domain-containing histidine kinase -
  R4702_RS08830 thrS 1721046..1722989 (-) 1944 WP_000608330.1 threonine--tRNA ligase -
  R4702_RS08835 - 1723047..1723223 (-) 177 Protein_1705 MazG-like protein -
  R4702_RS08840 - 1723230..1723370 (-) 141 WP_000422775.1 MazG-like protein -
  R4702_RS08845 - 1723801..1724001 (-) 201 WP_001834370.1 hypothetical protein -
  R4702_RS08850 - 1724240..1724870 (+) 631 Protein_1708 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=819201 R4702_RS08820 WP_000548991.1 1719353..1720030(+) (braR) [Streptococcus pneumoniae strain 16P4028]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=819201 R4702_RS08820 WP_000548991.1 1719353..1720030(+) (braR) [Streptococcus pneumoniae strain 16P4028]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTGTTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTCATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369