Detailed information NTG0818958

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAO34_RS10595
• Genome accession: NZ_CP123112
• Coordinates: 2155315..2156202 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain IT-MSSA46
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2150315..2161202

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAO34_RS10565 (QAO34_10530)	-	2151046..2151807 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAO34_RS10570 (QAO34_10535)	-	2152053..2152508 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAO34_RS10575 (QAO34_10540)	-	2152630..2152731 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAO34_RS10580 (QAO34_10545)	-	2152791..2154215 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAO34_RS10585 (QAO34_10550)	-	2154413..2154613 (+)	201	WP_000604723.1	hypothetical protein	-
QAO34_RS10590 (QAO34_10555)	braR	2154639..2155304 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAO34_RS10595 (QAO34_10560)	braS	2155315..2156202 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAO34_RS10600 (QAO34_10565)	-	2156310..2157065 (+)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
QAO34_RS10605 (QAO34_10570)	-	2157062..2159062 (+)	2001	WP_000776746.1	ABC transporter permease	-
QAO34_RS10610 (QAO34_10575)	-	2159726..2159839 (+)	114	WP_072384844.1	hypothetical protein	-
QAO34_RS10615 (QAO34_10580)	-	2160221..2160481 (+)	261	WP_072434822.1	hypothetical protein	-
QAO34_RS10620 (QAO34_10585)	-	2160491..2160988 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAO34_RS10625 (QAO34_10590)	-	2161096..2161184 (-)	89	Protein_2056	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=818958 QAO34_RS10595 WP_000143420.1 2155315..2156202(+) (braS) [Staphylococcus aureus strain IT-MSSA46]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818958 QAO34_RS10595 WP_000143420.1 2155315..2156202(+) (braS) [Staphylococcus aureus strain IT-MSSA46]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993