Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4713_RS07730 Genome accession   NZ_CP137103
Coordinates   1454124..1454756 (+) Length   210 a.a.
NCBI ID   WP_000698433.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 21334     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1449124..1459756
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4713_RS07705 mvaD 1449401..1450354 (+) 954 WP_000373456.1 diphosphomevalonate decarboxylase -
  R4713_RS07710 - 1450341..1451348 (+) 1008 WP_000562377.1 phosphomevalonate kinase -
  R4713_RS07715 fni 1451332..1452342 (+) 1011 WP_000210628.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4713_RS07720 liaF 1452420..1453118 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  R4713_RS07725 - 1453115..1454110 (+) 996 WP_000743662.1 sensor histidine kinase -
  R4713_RS07730 vraR 1454124..1454756 (+) 633 WP_000698433.1 response regulator transcription factor Regulator
  R4713_RS07735 - 1454757..1454999 (+) 243 Protein_1477 DNA alkylation repair protein -
  R4713_RS07740 - 1454924..1455526 (+) 603 Protein_1478 DNA alkylation repair protein -
  R4713_RS07745 - 1455985..1456587 (+) 603 Protein_1479 trypsin-like serine peptidase -
  R4713_RS07750 - 1456943..1457248 (+) 306 WP_001821501.1 tyrosine-type recombinase/integrase -
  R4713_RS07755 tig 1457442..1458725 (+) 1284 WP_000116462.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23539.00 Da        Isoelectric Point: 4.5739

>NTDB_id=818833 R4713_RS07730 WP_000698433.1 1454124..1454756(+) (vraR) [Streptococcus pneumoniae strain 21334]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQDEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=818833 R4713_RS07730 WP_000698433.1 1454124..1454756(+) (vraR) [Streptococcus pneumoniae strain 21334]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGATGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41