Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   QAO20_RS08380 Genome accession   NZ_CP123106
Coordinates   1742966..1743631 (+) Length   221 a.a.
NCBI ID   WP_000697883.1    Uniprot ID   A0A5F0HLH2
Organism   Staphylococcus aureus strain IT-MSSA50     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1737966..1748631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO20_RS08355 (QAO20_08315) - 1739378..1740139 (+) 762 WP_000323452.1 alpha/beta hydrolase -
  QAO20_RS08360 (QAO20_08320) - 1740380..1740835 (+) 456 WP_000106185.1 MarR family winged helix-turn-helix transcriptional regulator -
  QAO20_RS08365 (QAO20_08325) - 1740957..1741058 (+) 102 WP_000731972.1 SE2200 family small protein -
  QAO20_RS08370 (QAO20_08330) - 1741118..1742542 (-) 1425 WP_000953740.1 alkaline phosphatase -
  QAO20_RS08375 (QAO20_08335) - 1742740..1742940 (+) 201 WP_000604725.1 hypothetical protein -
  QAO20_RS08380 (QAO20_08340) braR 1742966..1743631 (+) 666 WP_000697883.1 nisin susceptibility-associated two-component system response regulator NsaR Regulator
  QAO20_RS08385 (QAO20_08345) braS 1743642..1744529 (+) 888 WP_000143430.1 nisin susceptibility-associated two-component system sensor histidine kinase NsaS Regulator
  QAO20_RS08390 (QAO20_08350) - 1744637..1745392 (+) 756 WP_000923769.1 ABC transporter ATP-binding protein -
  QAO20_RS08395 (QAO20_08355) - 1745389..1747389 (+) 2001 WP_000776748.1 ABC transporter permease -
  QAO20_RS08400 (QAO20_08360) - 1748048..1748161 (+) 114 WP_031918517.1 hypothetical protein -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 25433.52 Da        Isoelectric Point: 4.7961

>NTDB_id=818820 QAO20_RS08380 WP_000697883.1 1742966..1743631(+) (braR) [Staphylococcus aureus strain IT-MSSA50]
MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQPQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSR
IDNMDQIMAIQMGGDDFIEKPFNLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVGYKV

Nucleotide


Download         Length: 666 bp        

>NTDB_id=818820 QAO20_RS08380 WP_000697883.1 1742966..1743631(+) (braR) [Staphylococcus aureus strain IT-MSSA50]
ATGAAAATATTAATTGTTGAAGATGATTTTGTTATAGCAGAAAGTTTAGCATCTGAACTTAAAAAATGGAATTACGGTGT
TATTGTCGTTGAACAATTTGATGATATACTGTCTATCTTTAACCAACATCAGCCTCAGCTTGTATTGCTAGATATTAATT
TGCCAACGTTAAATGGTTTTCATTGGTGTCAAGAAATCCGAAAAACATCTAATGTGCCAATTATATTTATTAGTTCCCGT
ATTGATAATATGGACCAAATTATGGCAATACAAATGGGGGGAGATGATTTTATCGAAAAACCATTTAACTTGTCATTAAC
GATTGCCAAAATTCAAGCATTATTGAGACGAACTTATGACTTGTCAGTAGCTAATGATTCGATGACGGTTAAAGGTTGTA
CATTAATATTAGATGAAGCAAAAGTCGTGTATCAAGAACAAAACATACAGCTATCTTTGACTGAATTACAAATATTAAAG
TTATTATTTCAAAATGAAGATAAATATGTAAGTAGAACTGCTTTAATTGAAAAATGTTGGGAATCAGAAAACTTCATAGA
TGATAACACATTAGCTGTTAACATGACGCGCCTGCGTAAAAAATTAAATACTATTGGCGTTAATGATTTTATCATTACAA
AGAAAAATGTCGGATATAAAGTATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5F0HLH2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

99.548

100

0.995