Detailed information NTG0818576

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QAY74_RS10590
• Genome accession: NZ_CP123093
• Coordinates: 2156017..2156904 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain MRSA-EDCC5443
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2151017..2161904

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY74_RS10560 (QAY74_10535)	-	2151748..2152509 (+)	762	WP_000323451.1	alpha/beta hydrolase	-
QAY74_RS10565 (QAY74_10540)	-	2152755..2153210 (+)	456	WP_000106184.1	MarR family winged helix-turn-helix transcriptional regulator	-
QAY74_RS10570 (QAY74_10545)	-	2153332..2153433 (+)	102	WP_000731972.1	SE2200 family small protein	-
QAY74_RS10575 (QAY74_10550)	-	2153493..2154917 (-)	1425	WP_000953731.1	alkaline phosphatase	-
QAY74_RS10580 (QAY74_10555)	-	2155115..2155315 (+)	201	WP_000604723.1	hypothetical protein	-
QAY74_RS10585 (QAY74_10560)	braR	2155341..2156006 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QAY74_RS10590 (QAY74_10565)	braS	2156017..2156904 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QAY74_RS10595 (QAY74_10570)	-	2157012..2157767 (+)	756	WP_000923771.1	ABC transporter ATP-binding protein	-
QAY74_RS10600 (QAY74_10575)	-	2157764..2159764 (+)	2001	WP_052995994.1	FtsX-like permease family protein	-
QAY74_RS10605 (QAY74_10580)	-	2160428..2160541 (+)	114	WP_072384844.1	hypothetical protein	-
QAY74_RS10610 (QAY74_10585)	-	2160923..2161183 (+)	261	WP_072434822.1	hypothetical protein	-
QAY74_RS10615 (QAY74_10590)	-	2161193..2161690 (+)	498	WP_001065267.1	glutathione peroxidase	-
QAY74_RS10620 (QAY74_10595)	-	2161798..2161886 (-)	89	Protein_2058	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=818576 QAY74_RS10590 WP_000143420.1 2156017..2156904(+) (braS) [Staphylococcus aureus strain MRSA-EDCC5443]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=818576 QAY74_RS10590 WP_000143420.1 2156017..2156904(+) (braS) [Staphylococcus aureus strain MRSA-EDCC5443]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993