Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8619_RS07460 Genome accession   NZ_AP026918
Coordinates   1461818..1462495 (-) Length   225 a.a.
NCBI ID   WP_054384441.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1456818..1467495
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS07435 - 1456993..1457621 (-) 629 Protein_1468 NAD(P)-dependent oxidoreductase -
  R8619_RS07440 - 1457860..1458223 (+) 364 Protein_1469 hypothetical protein -
  R8619_RS07445 (PC0009_14730) - 1458480..1458803 (+) 324 WP_000422776.1 MazG-like protein -
  R8619_RS07450 (PC0009_14740) thrS 1458861..1460804 (+) 1944 WP_054384438.1 threonine--tRNA ligase -
  R8619_RS07455 (PC0009_14750) - 1460851..1461825 (-) 975 WP_054384440.1 sensor histidine kinase -
  R8619_RS07460 (PC0009_14760) braR 1461818..1462495 (-) 678 WP_054384441.1 response regulator transcription factor Regulator
  R8619_RS07465 (PC0009_14770) - 1462770..1463843 (+) 1074 WP_054384443.1 DUF2974 domain-containing protein -
  R8619_RS07470 (PC0009_14780) - 1463901..1464338 (-) 438 WP_054384444.1 Rrf2 family transcriptional regulator -
  R8619_RS07475 (PC0009_14790) - 1464414..1465256 (-) 843 WP_054384445.1 metallophosphoesterase -
  R8619_RS07480 (PC0009_14800) - 1465368..1466018 (+) 651 WP_054384446.1 metal-dependent transcriptional regulator -
  R8619_RS07485 (PC0009_14810) - 1466421..1466735 (+) 315 WP_000420682.1 YdcP family protein -
  R8619_RS07490 (PC0009_14820) - 1466751..1467137 (+) 387 WP_000985015.1 YdcP family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25922.08 Da        Isoelectric Point: 5.1362

>NTDB_id=81855 R8619_RS07460 WP_054384441.1 1461818..1462495(-) (braR) [Streptococcus pneumoniae strain PZ900700009]
MHKVLLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=81855 R8619_RS07460 WP_054384441.1 1461818..1462495(-) (braR) [Streptococcus pneumoniae strain PZ900700009]
ATGCACAAGGTTTTACTAGTAGAAGATGATCAGGTTATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTGCTGGTAGAAGACTTTATGGAAGTTTTAAGCCTTTTTGTCCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GACTGCCCTTGTTTAATGGCTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTGCCCATTATGTTTCTGTCTTCC
AGAGACCAAGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTTACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGACGAGAGTTTACTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTAAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTTTTATTTGAGCATGCGGGCAATATCGTAGCGCGTGATGACCTCATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACTCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAAGAACAGGGCTTGGTAGGGTTTATCGAGA
CCAAGAAAGGGATAGGGTATGGACTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364

Multiple sequence alignment