Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R4710_RS02515 Genome accession   NZ_CP137101
Coordinates   481316..481993 (-) Length   225 a.a.
NCBI ID   WP_050245211.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 476316..486993
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS02485 - 476491..477120 (-) 630 WP_000762090.1 NAD(P)-dependent oxidoreductase -
  R4710_RS02490 - 477356..477719 (+) 364 Protein_494 hypothetical protein -
  R4710_RS02495 - 477976..478116 (+) 141 WP_000422775.1 MazG-like protein -
  R4710_RS02500 - 478123..478299 (+) 177 WP_000166031.1 MazG-like protein -
  R4710_RS02505 thrS 478357..480300 (+) 1944 WP_000608337.1 threonine--tRNA ligase -
  R4710_RS02510 - 480349..481323 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  R4710_RS02515 braR 481316..481993 (-) 678 WP_050245211.1 response regulator transcription factor Regulator
  R4710_RS02520 - 482149..483222 (+) 1074 WP_001273813.1 DUF2974 domain-containing protein -
  R4710_RS02525 - 483313..483615 (-) 303 WP_000281595.1 hypothetical protein -
  R4710_RS02530 - 483684..484121 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R4710_RS02535 - 484197..485039 (-) 843 WP_000160933.1 metallophosphoesterase -
  R4710_RS02540 - 485151..485801 (+) 651 WP_000188504.1 metal-dependent transcriptional regulator -
  R4710_RS02545 - 485978..486655 (+) 678 WP_000260183.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25990.24 Da        Isoelectric Point: 5.1362

>NTDB_id=818528 R4710_RS02515 WP_050245211.1 481316..481993(-) (braR) [Streptococcus pneumoniae strain 16P2012-2]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQLEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=818528 R4710_RS02515 WP_050245211.1 481316..481993(-) (braR) [Streptococcus pneumoniae strain 16P2012-2]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTTGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

35.319

100

0.369