Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4703_RS08060 Genome accession   NZ_CP137100
Coordinates   1482946..1483578 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain LYP     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1477946..1488578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4703_RS08035 mvaD 1478224..1479177 (+) 954 WP_000373457.1 diphosphomevalonate decarboxylase -
  R4703_RS08040 - 1479164..1480171 (+) 1008 WP_000562441.1 phosphomevalonate kinase -
  R4703_RS08045 fni 1480155..1481165 (+) 1011 WP_000210617.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4703_RS08050 liaF 1481242..1481940 (+) 699 WP_001224639.1 cell wall-active antibiotics response protein LiaF -
  R4703_RS08055 - 1481937..1482932 (+) 996 WP_000743661.1 sensor histidine kinase -
  R4703_RS08060 vraR 1482946..1483578 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  R4703_RS08065 - 1483579..1483821 (+) 243 WP_001820556.1 DNA alkylation repair protein -
  R4703_RS08070 - 1483803..1484057 (+) 255 WP_050229268.1 DNA alkylation repair protein -
  R4703_RS11740 - 1484134..1484229 (+) 96 Protein_1546 DNA alkylation repair protein -
  R4703_RS08080 - 1484688..1485291 (+) 604 Protein_1547 trypsin-like serine peptidase -
  R4703_RS08085 - 1485593..1485985 (+) 393 WP_000378119.1 tyrosine-type recombinase/integrase -
  R4703_RS08090 tig 1486146..1487429 (+) 1284 WP_050201120.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=818477 R4703_RS08060 WP_000698432.1 1482946..1483578(+) (vraR) [Streptococcus pneumoniae strain LYP]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=818477 R4703_RS08060 WP_000698432.1 1482946..1483578(+) (vraR) [Streptococcus pneumoniae strain LYP]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTATTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTCATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41