Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QAO27_RS02165 Genome accession   NZ_CP123086
Coordinates   398605..399291 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain MSSA-ATCC29213     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 393605..404291
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO27_RS02130 (QAO27_02125) yqeH 394132..395232 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  QAO27_RS02135 (QAO27_02130) aroE 395246..396052 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  QAO27_RS02140 (QAO27_02135) yhbY 396056..396346 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  QAO27_RS02145 (QAO27_02140) nadD 396349..396918 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QAO27_RS02150 (QAO27_02145) yqeK 396908..397492 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QAO27_RS02155 (QAO27_02150) rsfS 397493..397846 (+) 354 WP_001088020.1 ribosome silencing factor -
  QAO27_RS02160 (QAO27_02155) - 397849..398565 (+) 717 WP_000084829.1 class I SAM-dependent DNA methyltransferase -
  QAO27_RS02165 (QAO27_02160) comEA 398605..399291 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  QAO27_RS02170 (QAO27_02165) - 399383..399844 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QAO27_RS02175 (QAO27_02170) comEC 399849..402050 (+) 2202 WP_001557362.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  QAO27_RS02180 (QAO27_02175) holA 402107..403081 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  QAO27_RS02185 (QAO27_02180) rpsT 403126..403377 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=818419 QAO27_RS02165 WP_001802022.1 398605..399291(+) (comEA) [Staphylococcus aureus strain MSSA-ATCC29213]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=818419 QAO27_RS02165 WP_001802022.1 398605..399291(+) (comEA) [Staphylococcus aureus strain MSSA-ATCC29213]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974