Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R4714_RS07555 Genome accession   NZ_CP137099
Coordinates   1414517..1415149 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain 20824-4     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1409517..1420149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS07530 mvaD 1409794..1410747 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  R4714_RS07535 - 1410734..1411741 (+) 1008 WP_050257858.1 phosphomevalonate kinase -
  R4714_RS07540 fni 1411725..1412735 (+) 1011 WP_050257857.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R4714_RS07545 liaF 1412813..1413511 (+) 699 WP_001224634.1 cell wall-active antibiotics response protein LiaF -
  R4714_RS07550 - 1413508..1414503 (+) 996 WP_000743669.1 sensor histidine kinase -
  R4714_RS07555 vraR 1414517..1415149 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  R4714_RS07560 - 1415224..1415918 (+) 695 Protein_1439 DNA alkylation repair protein -
  R4714_RS07565 - 1416068..1416307 (+) 240 WP_000754501.1 hypothetical protein -
  R4714_RS07570 cbpG 1416388..1417209 (+) 822 WP_001100143.1 choline-binding protein CbpG -
  R4714_RS07575 cbpF 1417228..1418250 (+) 1023 WP_050972238.1 choline-binding protein CbpF -
  R4714_RS07580 - 1418378..1419727 (-) 1350 Protein_1443 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=818355 R4714_RS07555 WP_000698434.1 1414517..1415149(+) (vraR) [Streptococcus pneumoniae strain 20824-4]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=818355 R4714_RS07555 WP_000698434.1 1414517..1415149(+) (vraR) [Streptococcus pneumoniae strain 20824-4]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGCTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41