Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   R4714_RS03925 Genome accession   NZ_CP137099
Coordinates   738852..739751 (-) Length   299 a.a.
NCBI ID   WP_000904867.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20824-4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 733852..744751
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4714_RS03900 rsmA 734182..735054 (-) 873 WP_001216856.1 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA -
  R4714_RS03905 - 735185..735493 (-) 309 WP_219576894.1 hypothetical protein -
  R4714_RS03910 - 735486..736127 (-) 642 WP_219576893.1 ABC transporter ATP-binding protein -
  R4714_RS03915 - 736129..738159 (-) 2031 WP_000825263.1 bacteriocin-associated integral membrane family protein -
  R4714_RS03920 - 738236..738532 (-) 297 WP_000815394.1 lactococcin 972 family bacteriocin -
  R4714_RS03925 comR 738852..739751 (-) 900 WP_000904867.1 helix-turn-helix domain-containing protein Regulator
  R4714_RS03930 rnmV 739823..740383 (-) 561 WP_000664448.1 ribonuclease M5 -
  R4714_RS03935 - 740383..741156 (-) 774 WP_000575607.1 TatD family hydrolase -
  R4714_RS03940 - 741462..742181 (-) 720 Protein_757 DUF1542 domain-containing protein -
  R4714_RS03945 rpmH 742390..742524 (-) 135 WP_000831905.1 50S ribosomal protein L34 -
  R4714_RS03950 - 742669..743883 (-) 1215 WP_000666469.1 pyridoxal phosphate-dependent aminotransferase -
  R4714_RS03955 - 744039..744332 (-) 294 WP_000977365.1 hypothetical protein -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35191.04 Da        Isoelectric Point: 5.0703

>NTDB_id=818308 R4714_RS03925 WP_000904867.1 738852..739751(-) (comR) [Streptococcus pneumoniae strain 20824-4]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide


Download         Length: 900 bp        

>NTDB_id=818308 R4714_RS03925 WP_000904867.1 738852..739751(-) (comR) [Streptococcus pneumoniae strain 20824-4]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(7-59)

ComR tetratricopeptide (ComR_TPR)

(70-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.755

98.328

0.371
  comR Streptococcus suis P1/7

37.801

97.324

0.368
  comR Streptococcus suis 05ZYH33

37.801

97.324

0.368