Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   QAO35_RS07600 Genome accession   NZ_CP123074
Coordinates   1508609..1509295 (+) Length   228 a.a.
NCBI ID   WP_001802022.1    Uniprot ID   A0A7U7EYP5
Organism   Staphylococcus aureus strain SW-MRSA61     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1503609..1514295
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QAO35_RS07565 (QAO35_07580) yqeH 1504136..1505236 (+) 1101 WP_001280137.1 ribosome biogenesis GTPase YqeH -
  QAO35_RS07570 (QAO35_07585) aroE 1505250..1506056 (+) 807 WP_000666757.1 shikimate dehydrogenase -
  QAO35_RS07575 (QAO35_07590) yhbY 1506060..1506350 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  QAO35_RS07580 (QAO35_07595) nadD 1506353..1506922 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  QAO35_RS07585 (QAO35_07600) yqeK 1506912..1507496 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  QAO35_RS07590 (QAO35_07605) rsfS 1507497..1507850 (+) 354 WP_001088020.1 ribosome silencing factor -
  QAO35_RS07595 (QAO35_07610) - 1507853..1508569 (+) 717 WP_000084830.1 class I SAM-dependent DNA methyltransferase -
  QAO35_RS07600 (QAO35_07615) comEA 1508609..1509295 (+) 687 WP_001802022.1 ComEA family DNA-binding protein Machinery gene
  QAO35_RS07605 (QAO35_07620) - 1509387..1509848 (+) 462 WP_000439693.1 ComE operon protein 2 -
  QAO35_RS07610 (QAO35_07625) - 1509853..1512055 (+) 2203 Protein_1455 DNA internalization-related competence protein ComEC/Rec2 -
  QAO35_RS07615 (QAO35_07630) holA 1512112..1513086 (+) 975 WP_001282563.1 DNA polymerase III subunit delta -
  QAO35_RS07620 (QAO35_07635) rpsT 1513131..1513382 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25900.65 Da        Isoelectric Point: 9.6751

>NTDB_id=818213 QAO35_RS07600 WP_001802022.1 1508609..1509295(+) (comEA) [Staphylococcus aureus strain SW-MRSA61]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=818213 QAO35_RS07600 WP_001802022.1 1508609..1509295(+) (comEA) [Staphylococcus aureus strain SW-MRSA61]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAGTGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAATAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGATGATGCAGATGTAAGTCGAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGAAGTAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EYP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus N315

100

100

1
  comEA Staphylococcus aureus MW2

97.368

100

0.974