Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8619_RS01910 Genome accession   NZ_AP026918
Coordinates   362918..363550 (+) Length   210 a.a.
NCBI ID   WP_000698434.1    Uniprot ID   Q9S1J7
Organism   Streptococcus pneumoniae strain PZ900700009     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 357918..368550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8619_RS01885 (PC0009_03630) mvaD 358196..359149 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  R8619_RS01890 (PC0009_03640) - 359136..360143 (+) 1008 WP_000562431.1 phosphomevalonate kinase -
  R8619_RS01895 (PC0009_03650) fni 360127..361137 (+) 1011 WP_000210621.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8619_RS01900 (PC0009_03660) liaF 361214..361912 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R8619_RS01905 (PC0009_03670) - 361909..362904 (+) 996 WP_000743671.1 sensor histidine kinase -
  R8619_RS01910 (PC0009_03680) vraR 362918..363550 (+) 633 WP_000698434.1 response regulator transcription factor Regulator
  R8619_RS01915 - 363626..364320 (+) 695 Protein_374 DNA alkylation repair protein -
  R8619_RS01920 (PC0009_03710) - 364470..364709 (+) 240 WP_000754501.1 hypothetical protein -
  R8619_RS01925 (PC0009_03720) cbpG 364790..365611 (+) 822 WP_001100142.1 choline-binding protein CbpG -
  R8619_RS01930 (PC0009_03730) cbpF 365630..366652 (+) 1023 WP_000765209.1 choline-binding protein CbpF -
  R8619_RS01935 - 366780..367926 (-) 1147 Protein_378 IS3 family transposase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23553.03 Da        Isoelectric Point: 4.5791

>NTDB_id=81805 R8619_RS01910 WP_000698434.1 362918..363550(+) (vraR) [Streptococcus pneumoniae strain PZ900700009]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=81805 R8619_RS01910 WP_000698434.1 362918..363550(+) (vraR) [Streptococcus pneumoniae strain PZ900700009]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGAATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAATATTCTTGCCAAACT
TGAAGTCAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTGGGGCAAGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9S1J7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment