Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   R0Q54_RS19985 Genome accession   NZ_CP136992
Coordinates   3774707..3776590 (+) Length   627 a.a.
NCBI ID   WP_069964159.1    Uniprot ID   -
Organism   Bacillus subtilis strain J46     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 3769707..3781590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R0Q54_RS19970 (R0Q54_19970) ymcA 3770744..3771175 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  R0Q54_RS19975 (R0Q54_19975) cotE 3771437..3771982 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  R0Q54_RS19980 (R0Q54_19980) hexA 3772115..3774691 (+) 2577 WP_046160418.1 DNA mismatch repair protein MutS Machinery gene
  R0Q54_RS19985 (R0Q54_19985) hexB 3774707..3776590 (+) 1884 WP_069964159.1 DNA mismatch repair endonuclease MutL Machinery gene
  R0Q54_RS19990 (R0Q54_19990) - 3777026..3777109 (+) 84 WP_235091748.1 XtrA/YqaO family protein -
  R0Q54_RS19995 (R0Q54_19995) - 3777152..3777403 (+) 252 Protein_3881 VWA domain-containing protein -
  R0Q54_RS20000 (R0Q54_20000) - 3777700..3777948 (+) 249 WP_031600520.1 hypothetical protein -
  R0Q54_RS20005 (R0Q54_20005) - 3777999..3778361 (-) 363 WP_033881685.1 Ig-like domain-containing protein -
  R0Q54_RS20010 (R0Q54_20010) istB 3778578..3779336 (-) 759 WP_014479891.1 IS21-like element helper ATPase IstB -
  R0Q54_RS20015 (R0Q54_20015) istA 3779333..3780880 (-) 1548 WP_014480339.1 IS21 family transposase -

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70600.48 Da        Isoelectric Point: 5.6795

>NTDB_id=817419 R0Q54_RS19985 WP_069964159.1 3774707..3776590(+) (hexB) [Bacillus subtilis strain J46]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHASSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPERKVPEKAHAPSYSPMKLSSVVKEPIDAEEELPPLQFDAPSI
VDQEQTLEVSDVSEELPETFEQECHEEQQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHRQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=817419 R0Q54_RS19985 WP_069964159.1 3774707..3776590(+) (hexB) [Bacillus subtilis strain J46]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGACGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGACATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGCGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAATGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGTGACGGA
ATTAAAGATGTATTTAAACAGCAGCAGCTGATTCCGAGTGCCCAGCTTCCGAAAAAATCGGCACCTGTTATCAAAAATGA
GCAACAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAGAAAAGTACCGGAAAAAGCGCATGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGATTGATGCGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCATCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACTGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCAGCCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTGTATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAAGTGCAGGATATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAGACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTTATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.201

100

0.466