Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   R8522_RS09850 Genome accession   NZ_AP026916
Coordinates   1911840..1912460 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0H2URP6
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1906840..1917460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS09825 (PC0006_19790) recA 1907217..1908383 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  R8522_RS09830 (PC0006_19800) cinA 1908438..1909694 (-) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  R8522_RS09835 (PC0006_19810) brpA 1909779..1910795 (-) 1017 WP_054367130.1 biofilm formation/cell division transcriptional regulator BrpA -
  R8522_RS09840 (PC0006_19820) - 1910803..1911321 (-) 519 WP_050281538.1 GNAT family N-acetyltransferase -
  R8522_RS09845 (PC0006_19830) tsaE 1911311..1911754 (-) 444 WP_000288236.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  R8522_RS09850 (PC0006_19840) comM 1911840..1912460 (-) 621 WP_000839908.1 hypothetical protein Regulator
  R8522_RS09855 (PC0006_19850) - 1912982..1914328 (+) 1347 WP_061372817.1 IS1380-like element ISSpn5 family transposase -
  R8522_RS09860 (PC0006_19860) - 1914555..1915418 (-) 864 WP_001093620.1 helix-turn-helix domain-containing protein -
  R8522_RS09865 (PC0006_19870) - 1915610..1915780 (+) 171 WP_001227862.1 PhrA family quorum-sensing system peptide -
  R8522_RS09870 (PC0006_19880) pneA1 1915883..1916107 (+) 225 WP_000181086.1 two-peptide bacteriocin subunit PneA1 -
  R8522_RS09875 (PC0006_19890) pneA2 1916114..1916302 (+) 189 WP_000786759.1 two-peptide bacteriocin subunit PneA2 -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=81638 R8522_RS09850 WP_000839908.1 1911840..1912460(-) (comM) [Streptococcus pneumoniae strain PZ900700006]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=81638 R8522_RS09850 WP_000839908.1 1911840..1912460(-) (comM) [Streptococcus pneumoniae strain PZ900700006]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2URP6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment