Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8522_RS08215 Genome accession   NZ_AP026916
Coordinates   1609072..1609749 (-) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700006     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1604072..1614749
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8522_RS08190 (PC0006_16760) - 1604235..1604864 (-) 630 WP_054367381.1 NAD(P)-dependent oxidoreductase -
  R8522_RS08195 - 1605101..1605301 (+) 201 WP_001845636.1 hypothetical protein -
  R8522_RS08200 (PC0006_16770) - 1605732..1606055 (+) 324 Protein_1626 MazG-like protein -
  R8522_RS08205 (PC0006_16780) thrS 1606113..1608056 (+) 1944 WP_054367382.1 threonine--tRNA ligase -
  R8522_RS08210 (PC0006_16790) - 1608105..1609079 (-) 975 WP_000887953.1 HAMP domain-containing histidine kinase -
  R8522_RS08215 (PC0006_16800) braR 1609072..1609749 (-) 678 WP_000548961.1 response regulator transcription factor Regulator
  R8522_RS08220 (PC0006_16810) - 1609905..1610978 (+) 1074 WP_001273813.1 DUF2974 domain-containing protein -
  R8522_RS08225 - 1611069..1611371 (-) 303 WP_000281606.1 hypothetical protein -
  R8522_RS08230 (PC0006_16820) - 1611439..1611876 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R8522_RS08235 (PC0006_16830) - 1611952..1612794 (-) 843 WP_054367383.1 metallophosphoesterase -
  R8522_RS08240 (PC0006_16840) - 1612906..1613556 (+) 651 WP_000188498.1 metal-dependent transcriptional regulator -
  R8522_RS08245 (PC0006_16850) - 1613733..1614245 (+) 513 WP_054367384.1 hypothetical protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=81618 R8522_RS08215 WP_000548961.1 1609072..1609749(-) (braR) [Streptococcus pneumoniae strain PZ900700006]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=81618 R8522_RS08215 WP_000548961.1 1609072..1609749(-) (braR) [Streptococcus pneumoniae strain PZ900700006]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCAGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364