Detailed information NTG0815813

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QAY83_RS06595
• Genome accession: NZ_CP122484
• Coordinates: 1327996..1329039 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain SW-MSSA63
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1322996..1334039

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QAY83_RS06565 (QAY83_06555)	-	1323418..1324674 (-)	1257	WP_072419726.1	aminopeptidase	-
QAY83_RS06570 (QAY83_06560)	-	1324677..1324877 (-)	201	WP_000180460.1	DUF1128 family protein	-
QAY83_RS06575 (QAY83_06565)	-	1325024..1325488 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QAY83_RS06580 (QAY83_06570)	-	1325495..1325770 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QAY83_RS06585 (QAY83_06575)	-	1326048..1327265 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
QAY83_RS06590 (QAY83_06580)	vraR	1327377..1328006 (-)	630	WP_000153536.1	two-component system response regulator VraR	Regulator
QAY83_RS06595 (QAY83_06585)	vraS	1327996..1329039 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QAY83_RS06600 (QAY83_06590)	liaF	1329036..1329737 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QAY83_RS06605 (QAY83_06595)	-	1329752..1330138 (-)	387	WP_001110179.1	hypothetical protein	-
QAY83_RS06610 (QAY83_06600)	map	1330355..1331113 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QAY83_RS06615 (QAY83_06605)	-	1331644..1332630 (+)	987	WP_000999713.1	FUSC family protein	-
QAY83_RS06620 (QAY83_06610)	-	1333120..1333533 (-)	414	WP_001566709.1	hypothetical protein	-
QAY83_RS06625 (QAY83_06615)	-	1333562..1333672 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=815813 QAY83_RS06595 WP_001017131.1 1327996..1329039(-) (vraS) [Staphylococcus aureus strain SW-MSSA63]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=815813 QAY83_RS06595 WP_001017131.1 1327996..1329039(-) (vraS) [Staphylococcus aureus strain SW-MSSA63]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTAATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGCATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTGGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1