Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R1Y80_RS35220 Genome accession   NZ_CP136798
Coordinates   7927212..7927880 (-) Length   222 a.a.
NCBI ID   WP_100560662.1    Uniprot ID   -
Organism   Streptomyces sp. JL1001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7922212..7932880
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y80_RS35180 (R1Y80_35150) - 7922988..7923176 (-) 189 Protein_6946 XRE family transcriptional regulator -
  R1Y80_RS35185 (R1Y80_35155) - 7923345..7923950 (+) 606 WP_128806746.1 hypothetical protein -
  R1Y80_RS35190 (R1Y80_35160) - 7924114..7924272 (-) 159 WP_176725661.1 hypothetical protein -
  R1Y80_RS35195 (R1Y80_35165) - 7924325..7924542 (-) 218 Protein_6949 DUF5133 domain-containing protein -
  R1Y80_RS35200 (R1Y80_35170) - 7925068..7925265 (+) 198 WP_176725662.1 hypothetical protein -
  R1Y80_RS35205 (R1Y80_35175) - 7925511..7925772 (+) 262 Protein_6951 transposase family protein -
  R1Y80_RS35210 (R1Y80_35180) - 7925888..7926400 (+) 513 WP_128806747.1 DUF5959 family protein -
  R1Y80_RS35215 (R1Y80_35185) - 7926822..7927100 (-) 279 WP_354598839.1 hypothetical protein -
  R1Y80_RS35220 (R1Y80_35190) vraR 7927212..7927880 (-) 669 WP_100560662.1 response regulator transcription factor Regulator
  R1Y80_RS35225 (R1Y80_35195) - 7927877..7929055 (-) 1179 WP_354595998.1 histidine kinase -
  R1Y80_RS35230 (R1Y80_35200) - 7929093..7929605 (-) 513 WP_354595997.1 MarR family winged helix-turn-helix transcriptional regulator -
  R1Y80_RS35235 (R1Y80_35205) - 7929763..7930680 (+) 918 WP_354598840.1 SDR family NAD(P)-dependent oxidoreductase -
  R1Y80_RS35240 (R1Y80_35210) - 7930741..7931367 (+) 627 WP_354595995.1 NAD(P)H-binding protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23695.20 Da        Isoelectric Point: 5.0769

>NTDB_id=815600 R1Y80_RS35220 WP_100560662.1 7927212..7927880(-) (vraR) [Streptomyces sp. JL1001]
MTIKILLADDQELVRTGFKILVNSTPDMEVVAEASDGREAVRLAPAADVVLMDIRMPGFDGLTATQQITSALPDVRVLVL
TTFEVDEYVFSALRNGASGFLGKGVHPGELQDAIRLVAAGEQLLSPSATRALISRFLRGPAQDADTAAERLATLTGRERE
ILVLVAAGLSNDQIAQRLGISPLTAKTHVNRTQAKLDAHDRAQLVMLAYETGLVTAGARPTL

Nucleotide


Download         Length: 669 bp        

>NTDB_id=815600 R1Y80_RS35220 WP_100560662.1 7927212..7927880(-) (vraR) [Streptomyces sp. JL1001]
ATGACCATCAAGATCCTTCTCGCGGACGACCAGGAACTGGTCCGCACCGGTTTCAAGATCCTGGTGAACTCCACCCCCGA
CATGGAAGTGGTCGCCGAAGCATCCGACGGCCGCGAAGCGGTCCGCCTCGCCCCGGCCGCCGACGTCGTGCTGATGGACA
TCCGCATGCCGGGCTTCGACGGCCTGACCGCCACCCAGCAGATCACCTCCGCCCTGCCCGACGTGCGCGTGCTGGTGCTG
ACCACCTTCGAGGTCGACGAATACGTCTTCAGCGCGCTGCGCAACGGCGCCAGCGGCTTCCTCGGCAAGGGCGTCCACCC
CGGCGAACTGCAGGACGCGATCCGGCTAGTCGCCGCTGGCGAGCAGCTGCTGTCCCCGTCGGCCACGCGTGCGCTGATCA
GCCGGTTCCTGCGCGGCCCCGCCCAGGACGCCGACACCGCTGCCGAGCGGCTGGCCACTCTCACCGGGCGCGAGCGCGAG
ATCCTCGTCCTGGTCGCGGCCGGGCTCAGCAACGACCAGATCGCCCAGCGGCTCGGCATCAGCCCGCTCACCGCCAAGAC
CCACGTGAACCGCACCCAGGCCAAACTCGATGCCCACGACCGGGCCCAGCTCGTCATGCTCGCCTACGAAACCGGCCTGG
TCACCGCCGGTGCACGCCCGACGCTGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(153-208)

Response regulator receiver domain (Response_reg)

(5-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.615

98.198

0.369
  degU Bacillus subtilis subsp. subtilis str. 168

36.771

100

0.369