Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R1Y80_RS19785 Genome accession   NZ_CP136798
Coordinates   4349930..4350598 (+) Length   222 a.a.
NCBI ID   WP_006126329.1    Uniprot ID   A0A2U8NNZ9
Organism   Streptomyces sp. JL1001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4344930..4355598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y80_RS19765 (R1Y80_19740) kynU 4345150..4346388 (+) 1239 WP_354597586.1 kynureninase -
  R1Y80_RS19770 (R1Y80_19745) - 4346576..4347499 (+) 924 WP_354597587.1 alpha/beta hydrolase -
  R1Y80_RS19775 (R1Y80_19750) - 4347657..4348484 (+) 828 WP_354597588.1 NAD(P)H-binding protein -
  R1Y80_RS19780 (R1Y80_19755) - 4348593..4349933 (+) 1341 WP_100559711.1 histidine kinase -
  R1Y80_RS19785 (R1Y80_19760) vraR 4349930..4350598 (+) 669 WP_006126329.1 response regulator transcription factor Regulator
  R1Y80_RS19790 (R1Y80_19765) - 4350652..4351857 (+) 1206 WP_032776773.1 cytochrome P450 -
  R1Y80_RS19795 (R1Y80_19770) - 4351883..4352218 (-) 336 WP_354598924.1 hypothetical protein -
  R1Y80_RS19800 (R1Y80_19775) - 4352323..4352595 (-) 273 WP_069735586.1 DUF1876 domain-containing protein -
  R1Y80_RS19805 (R1Y80_19780) - 4352645..4353529 (-) 885 WP_354597589.1 diacylglycerol kinase -
  R1Y80_RS19810 (R1Y80_19785) - 4353716..4354999 (+) 1284 WP_026237801.1 adenylosuccinate synthase -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24047.84 Da        Isoelectric Point: 4.7242

>NTDB_id=815567 R1Y80_RS19785 WP_006126329.1 4349930..4350598(+) (vraR) [Streptomyces sp. JL1001]
MSDTDIRVLIVDDQMMVREGFSVLLNAMPGITVVGEALDGRQALDQVAALRPDVVLMDIRMPEMNGIEATREIVARDADA
KVLVLTTFDLDEYVYQALRAGASGFLLKDASARQLADGVRVVASGEALLAPTVTRRLITEFSKLAETPRPPALARIGDLT
ERETEVLVLIAQGLSNAEIASHLIVAESTIKTHVSRILVKLGLRDRTQAAVFAYEARLVTPG

Nucleotide


Download         Length: 669 bp        

>NTDB_id=815567 R1Y80_RS19785 WP_006126329.1 4349930..4350598(+) (vraR) [Streptomyces sp. JL1001]
ATGAGCGACACCGACATCCGGGTCCTGATCGTCGACGACCAGATGATGGTCCGCGAGGGCTTCTCGGTCCTGCTCAACGC
GATGCCCGGGATCACCGTCGTGGGCGAGGCGCTGGACGGCCGGCAGGCGCTCGACCAGGTCGCCGCCCTGCGCCCGGACG
TCGTCCTGATGGACATCCGCATGCCCGAGATGAACGGCATCGAGGCGACCCGCGAGATCGTCGCCCGGGACGCCGACGCG
AAGGTCCTGGTGCTGACGACCTTCGACCTCGACGAGTACGTCTACCAGGCGCTGCGGGCCGGGGCCTCGGGCTTCCTTCT
CAAGGACGCCTCGGCCCGGCAGCTCGCCGACGGCGTGCGGGTGGTGGCCTCGGGCGAGGCGCTGCTCGCCCCGACGGTCA
CCCGGCGCCTGATCACCGAGTTCTCCAAGCTCGCGGAGACGCCGCGCCCGCCCGCCCTGGCGCGGATCGGGGATCTCACC
GAGCGCGAGACGGAGGTGCTCGTCCTCATCGCACAGGGGCTCTCCAACGCGGAGATCGCCTCGCATCTGATCGTCGCCGA
GTCCACGATCAAGACGCATGTGAGCCGCATCCTGGTGAAGCTGGGGCTGCGCGACCGGACGCAGGCGGCGGTGTTCGCGT
ACGAGGCGCGGCTGGTCACCCCGGGGTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(159-213)

Response regulator receiver domain (Response_reg)

(8-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U8NNZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.925

96.396

0.423
  degU Bacillus subtilis subsp. subtilis str. 168

42.466

98.649

0.419