Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R1Y80_RS06725 Genome accession   NZ_CP136798
Coordinates   1504509..1505153 (-) Length   214 a.a.
NCBI ID   WP_006123560.1    Uniprot ID   A0A5D4HJE9
Organism   Streptomyces sp. JL1001     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1499509..1510153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R1Y80_RS06695 (R1Y80_06680) - 1499641..1500408 (-) 768 WP_100565045.1 sulfite exporter TauE/SafE family protein -
  R1Y80_RS06700 (R1Y80_06685) - 1500493..1501473 (-) 981 WP_032761334.1 SPFH domain-containing protein -
  R1Y80_RS06705 (R1Y80_06690) - 1501638..1502066 (-) 429 WP_030713610.1 NfeD family protein -
  R1Y80_RS06710 (R1Y80_06695) - 1502173..1502970 (-) 798 WP_032761336.1 ABC transporter ATP-binding protein -
  R1Y80_RS06715 (R1Y80_06700) - 1503115..1503900 (+) 786 WP_032761338.1 hypothetical protein -
  R1Y80_RS06720 (R1Y80_06705) - 1504110..1504361 (-) 252 WP_030586340.1 chaplin family protein -
  R1Y80_RS06725 (R1Y80_06710) vraR 1504509..1505153 (-) 645 WP_006123560.1 response regulator transcription factor Regulator
  R1Y80_RS06730 (R1Y80_06715) - 1505146..1506291 (-) 1146 WP_354596602.1 GAF domain-containing sensor histidine kinase -
  R1Y80_RS06735 (R1Y80_06720) - 1506535..1507257 (+) 723 WP_100565046.1 SDR family oxidoreductase -
  R1Y80_RS06740 (R1Y80_06725) - 1507287..1508513 (+) 1227 WP_354596603.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase -
  R1Y80_RS06745 (R1Y80_06730) - 1508786..1509562 (+) 777 WP_100564995.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23141.45 Da        Isoelectric Point: 5.3843

>NTDB_id=815538 R1Y80_RS06725 WP_006123560.1 1504509..1505153(-) (vraR) [Streptomyces sp. JL1001]
MADKIIRVLLVDDHQVVRRGLRTFLEIQEDIEVVGEASDGAEGVARTEELRPDVVLMDIKMPGTDGIEALRRLRELDNPA
KVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIRSVHAGHVLLQPEVAGALLAQEDTGTGTGRGSTLTEREREV
LGLIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGAVG

Nucleotide


Download         Length: 645 bp        

>NTDB_id=815538 R1Y80_RS06725 WP_006123560.1 1504509..1505153(-) (vraR) [Streptomyces sp. JL1001]
GTGGCTGACAAGATCATCAGGGTGCTGCTGGTCGACGACCACCAGGTGGTCCGCCGCGGACTGCGCACGTTCCTGGAGAT
CCAGGAGGACATAGAGGTCGTCGGCGAGGCGTCCGACGGTGCGGAGGGCGTGGCCCGGACCGAGGAACTGCGCCCCGACG
TCGTGCTCATGGACATCAAGATGCCCGGCACCGACGGCATCGAGGCGCTGCGCCGCCTGCGCGAGCTCGACAACCCGGCC
AAGGTCCTCATCGTCACCAGCTTCACCGAACAGCGCACCGTGGTCCCCGCCCTGCGCGCCGGAGCCTCCGGTTACGTCTA
CAAGGACGTCGACCCGGACGCCCTGGCGGGGGCGATCCGCTCCGTCCACGCCGGACACGTCCTGCTCCAGCCCGAGGTCG
CCGGCGCCCTCCTCGCCCAGGAGGACACGGGCACCGGCACGGGGCGGGGGAGCACCCTCACCGAACGGGAACGCGAGGTC
CTCGGCCTCATCGCGGACGGCCGTTCGAACCGGGAGATCGCCCGGGCCCTCGTCCTCTCCGAGAAGACGGTCAAGACCCA
CGTCTCGAACATCCTGATGAAACTCGACCTGGCCGACCGTACCCAGGCGGCGCTGTGGGCGGTACGCCACGGAGCGGTGG
GCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(8-119)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5D4HJE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.976

97.664

0.439
  degU Bacillus subtilis subsp. subtilis str. 168

39.462

100

0.411