Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R0492_RS17545 Genome accession   NZ_CP136649
Coordinates   3347366..3348001 (-) Length   211 a.a.
NCBI ID   WP_003185124.1    Uniprot ID   Q65F45
Organism   Bacillus licheniformis strain NXU98     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3342366..3353001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R0492_RS17520 - 3342982..3343149 (-) 168 WP_003185114.1 YvzF family protein -
  R0492_RS17525 - 3343273..3344715 (+) 1443 WP_016885760.1 spore germination protein -
  R0492_RS17530 - 3344684..3345784 (+) 1101 WP_016885759.1 endospore germination permease -
  R0492_RS17535 - 3345781..3346902 (+) 1122 WP_016885758.1 Ger(x)C family spore germination protein -
  R0492_RS17540 - 3346946..3347329 (+) 384 WP_161658311.1 hypothetical protein -
  R0492_RS17545 vraR 3347366..3348001 (-) 636 WP_003185124.1 response regulator transcription factor Regulator
  R0492_RS17550 liaS 3348005..3349069 (-) 1065 WP_003185128.1 two-component system sensor histidine kinase LiaS -
  R0492_RS17555 liaF 3349066..3349797 (-) 732 WP_003185130.1 cell wall-active antibiotics response protein LiaF -
  R0492_RS17560 - 3349828..3350691 (-) 864 WP_003185131.1 DUF4097 domain-containing protein -
  R0492_RS17565 liaH 3350797..3351480 (-) 684 WP_009329563.1 stress responsive protein LiaH -
  R0492_RS17570 - 3351501..3351887 (-) 387 WP_003185133.1 protein liaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.83 Da        Isoelectric Point: 5.1797

>NTDB_id=815423 R0492_RS17545 WP_003185124.1 3347366..3348001(-) (vraR) [Bacillus licheniformis strain NXU98]
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Nucleotide


Download         Length: 636 bp        

>NTDB_id=815423 R0492_RS17545 WP_003185124.1 3347366..3348001(-) (vraR) [Bacillus licheniformis strain NXU98]
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACGGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65F45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.052

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.389