Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   RX583_RS17950 Genome accession   NZ_CP136402
Coordinates   3395823..3396458 (-) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis subsp. subtilis str. 168     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3390823..3401458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RX583_RS17930 (RX583_17930) yvzF 3391880..3392065 (-) 186 WP_003244599.1 YvzF family protein -
  RX583_RS17935 (RX583_17935) gerAA 3392183..3393631 (+) 1449 WP_009969097.1 spore germination receptor protein GerAA -
  RX583_RS17940 (RX583_17940) gerAB 3393600..3394697 (+) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  RX583_RS17945 (RX583_17945) gerAC 3394694..3395815 (+) 1122 WP_009968146.1 spore germination receptor protein GerAC -
  RX583_RS17950 (RX583_17950) vraR 3395823..3396458 (-) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  RX583_RS17955 (RX583_17955) liaS 3396436..3397518 (-) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  RX583_RS17960 (RX583_17960) liaF 3397515..3398240 (-) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  RX583_RS17965 (RX583_17965) liaG 3398274..3399146 (-) 873 WP_003244420.1 DUF4097 domain-containing protein -
  RX583_RS17970 (RX583_17970) liaH 3399247..3399924 (-) 678 WP_003243047.1 stress responsive protein LiaH -
  RX583_RS17975 (RX583_17975) liaI 3399951..3400331 (-) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=814588 RX583_RS17950 WP_003243201.1 3395823..3396458(-) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=814588 RX583_RS17950 WP_003243201.1 3395823..3396458(-) (vraR) [Bacillus subtilis subsp. subtilis str. 168]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408