Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   R8474_RS02735 Genome accession   NZ_AP026914
Coordinates   535711..536388 (+) Length   225 a.a.
NCBI ID   WP_000548961.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 530711..541388
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS02700 (PC0003_05190) - 530783..531169 (-) 387 WP_000985015.1 YdcP family protein -
  R8474_RS02705 (PC0003_05200) - 531185..531499 (-) 315 WP_000420682.1 YdcP family protein -
  R8474_RS02710 (PC0003_05210) - 531903..532553 (-) 651 WP_081573873.1 metal-dependent transcriptional regulator -
  R8474_RS02715 (PC0003_05220) - 532665..533507 (+) 843 WP_061755538.1 metallophosphoesterase -
  R8474_RS02720 (PC0003_05230) - 533583..534020 (+) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  R8474_RS02725 (PC0003_05240) - 534089..534391 (+) 303 WP_000281601.1 hypothetical protein -
  R8474_RS02730 (PC0003_05250) - 534482..535555 (-) 1074 WP_050218598.1 DUF2974 domain-containing protein -
  R8474_RS02735 (PC0003_05260) braR 535711..536388 (+) 678 WP_000548961.1 response regulator transcription factor Regulator
  R8474_RS02740 (PC0003_05270) - 536381..537355 (+) 975 WP_000887954.1 HAMP domain-containing histidine kinase -
  R8474_RS02745 (PC0003_05280) thrS 537404..539347 (-) 1944 WP_081573872.1 threonine--tRNA ligase -
  R8474_RS02750 (PC0003_05290) - 539405..539728 (-) 324 Protein_542 MazG-like protein -
  R8474_RS02755 - 539985..540348 (-) 364 Protein_543 hypothetical protein -
  R8474_RS02760 (PC0003_05300) - 540585..541214 (+) 630 WP_000762081.1 NAD(P)-dependent oxidoreductase -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25950.13 Da        Isoelectric Point: 5.1362

>NTDB_id=81341 R8474_RS02735 WP_000548961.1 535711..536388(+) (braR) [Streptococcus pneumoniae strain PZ900700003]
MHKILLIEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=81341 R8474_RS02735 WP_000548961.1 535711..536388(+) (braR) [Streptococcus pneumoniae strain PZ900700003]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

48.624

96.889

0.471
  vicR Streptococcus mutans UA159

34.894

100

0.364

Multiple sequence alignment