Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   R8474_RS01805 Genome accession   NZ_AP026914
Coordinates   349855..350487 (+) Length   210 a.a.
NCBI ID   WP_000698432.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700003     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 344855..355487
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8474_RS01780 (PC0003_03440) mvaD 345132..346085 (+) 954 WP_000373458.1 diphosphomevalonate decarboxylase -
  R8474_RS01785 (PC0003_03450) - 346072..347079 (+) 1008 WP_081573893.1 phosphomevalonate kinase -
  R8474_RS01790 (PC0003_03460) fni 347063..348073 (+) 1011 WP_000210629.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  R8474_RS01795 (PC0003_03470) liaF 348151..348849 (+) 699 WP_001224637.1 cell wall-active antibiotics response protein LiaF -
  R8474_RS01800 (PC0003_03480) - 348846..349841 (+) 996 WP_000743663.1 sensor histidine kinase -
  R8474_RS01805 (PC0003_03490) vraR 349855..350487 (+) 633 WP_000698432.1 response regulator transcription factor Regulator
  R8474_RS01810 - 350488..350730 (+) 243 Protein_354 DNA alkylation repair protein -
  R8474_RS01815 - 350655..351257 (+) 603 Protein_355 DNA alkylation repair protein -
  R8474_RS01820 (PC0003_03520) - 351716..352318 (+) 603 Protein_356 trypsin-like serine peptidase -
  R8474_RS01825 (PC0003_03530) - 352674..353012 (+) 339 WP_025172171.1 tyrosine-type recombinase/integrase -
  R8474_RS01830 (PC0003_03540) tig 353173..354456 (+) 1284 WP_000116465.1 trigger factor -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23562.04 Da        Isoelectric Point: 4.6491

>NTDB_id=81335 R8474_RS01805 WP_000698432.1 349855..350487(+) (vraR) [Streptococcus pneumoniae strain PZ900700003]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLDAGAKGYMLKTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGHEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=81335 R8474_RS01805 WP_000698432.1 349855..350487(+) (vraR) [Streptococcus pneumoniae strain PZ900700003]
ATGAAAATTTTACTAGTAGATGACCATGAAATGGTCCGTTTGGGTTTGAAAAGCTACTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGTGAGGCGTCCAACGGGTCTCAAGGGATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCAATCCTTAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTATTTGGACAATGAAAAAATCATGCCAGTCTTAGATGCTGGTGCCAAAGGCTATATGCTCAAGACTTCTAGTGC
AGATGAATTGCTTCATGCCGTCAGTAAGGTAGCTGCTGGCGAGCTGGCCATTGAGCAAGAGGTTAGCAAGAAGGTTGAAT
ACCACCGCAATCATATGGAACTTCATGAAGAATTGACTGCGCGTGAGCGAGATGTTCTCCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGCATCGCAGATGACCTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATTCTTGCCAAACT
TGAAGTTAGCGATCGTACCCAGGCGGCTGTCTATGCCTTTCAGCACCATTTGGTCGGGCATGAGGAGTTTTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment