Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   QA712_RS05315 Genome accession   NZ_CP121539
Coordinates   954952..955653 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain MA5     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 949952..960653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA712_RS05295 (QA712_05280) - 950063..951280 (-) 1218 WP_058208332.1 cysteine desulfurase -
  QA712_RS05300 (QA712_05285) sufD 951280..952539 (-) 1260 WP_372757935.1 Fe-S cluster assembly protein SufD -
  QA712_RS05305 (QA712_05290) sufC 952673..953443 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  QA712_RS05310 (QA712_05295) - 953606..954949 (-) 1344 WP_311802963.1 MraY family glycosyltransferase -
  QA712_RS05315 (QA712_05300) mecA 954952..955653 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  QA712_RS05320 (QA712_05305) - 955782..956516 (-) 735 WP_029344350.1 amino acid ABC transporter ATP-binding protein -
  QA712_RS05325 (QA712_05310) - 956516..957202 (-) 687 WP_372757847.1 amino acid ABC transporter permease -
  QA712_RS05330 (QA712_05315) - 957349..958257 (-) 909 Protein_923 diacylglycerol/lipid kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=812859 QA712_RS05315 WP_004255173.1 954952..955653(-) (mecA) [Lactococcus lactis strain MA5]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=812859 QA712_RS05315 WP_004255173.1 954952..955653(-) (mecA) [Lactococcus lactis strain MA5]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGACATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97