Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   F6I35_RS02600 Genome accession   NZ_CP136160
Coordinates   468397..469029 (+) Length   210 a.a.
NCBI ID   WP_024052105.1    Uniprot ID   A0A413KQW8
Organism   Streptococcus anginosus strain UMB8616     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 463397..474029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F6I35_RS02580 (F6I35_0002580) - 463833..464573 (+) 741 WP_022526377.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  F6I35_RS02585 (F6I35_0002585) stkP 464570..466444 (+) 1875 WP_024052108.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  F6I35_RS02590 (F6I35_0002590) liaF 466705..467403 (+) 699 WP_150866975.1 cell wall-active antibiotics response protein LiaF -
  F6I35_RS02595 (F6I35_0002595) - 467400..468395 (+) 996 WP_150866973.1 sensor histidine kinase -
  F6I35_RS02600 (F6I35_0002600) vraR 468397..469029 (+) 633 WP_024052105.1 response regulator transcription factor Regulator
  F6I35_RS02605 (F6I35_0002605) - 469069..470469 (+) 1401 WP_070241554.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  F6I35_RS02610 (F6I35_0002610) - 470471..470842 (+) 372 WP_024052103.1 S1 RNA-binding domain-containing protein -
  F6I35_RS02615 (F6I35_0002615) - 470976..471293 (-) 318 WP_024052102.1 DUF960 domain-containing protein -
  F6I35_RS02620 (F6I35_0002620) - 471413..471946 (-) 534 WP_024052101.1 DUF402 domain-containing protein -
  F6I35_RS02625 (F6I35_0002625) recX 472024..472809 (-) 786 WP_042754014.1 recombination regulator RecX -
  F6I35_RS02630 (F6I35_0002630) - 472873..473649 (-) 777 WP_024052099.1 aminoglycoside 3'-phosphotransferase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23718.25 Da        Isoelectric Point: 4.6571

>NTDB_id=812830 F6I35_RS02600 WP_024052105.1 468397..469029(+) (vraR) [Streptococcus anginosus strain UMB8616]
MQILLVDDHEMVRLGLKGYLDLQDDVDVVAEASNGREGVERALELRPDVIMMDIVMPEMSGIEATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAKGYMLKTSSADDILRAVRKVAKGELAIETEVSQKVEYHRNHIELHEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDI

Nucleotide


Download         Length: 633 bp        

>NTDB_id=812830 F6I35_RS02600 WP_024052105.1 468397..469029(+) (vraR) [Streptococcus anginosus strain UMB8616]
ATGCAGATTTTATTAGTAGATGACCATGAAATGGTAAGACTTGGCTTAAAAGGTTATTTGGATTTACAAGACGATGTGGA
TGTAGTGGCAGAAGCTTCAAATGGTCGCGAAGGAGTTGAAAGAGCTTTGGAGTTGCGTCCAGATGTGATTATGATGGACA
TTGTCATGCCTGAAATGAGTGGGATTGAAGCGACACTTGCTATTTTAAAAGAATGGCCTGAAGCTAAAATTCTCATTTTG
ACTTCTTATTTGGATAATGAAAAAATTTATCCGGTTTTAGATGCGGGTGCTAAAGGATATATGCTCAAAACTTCTAGCGC
GGATGATATTTTACGAGCGGTCCGAAAAGTAGCCAAGGGTGAACTTGCTATTGAAACAGAAGTCAGCCAAAAAGTAGAAT
ATCATCGAAATCATATTGAATTGCACGAAGATTTGACTGCGCGTGAGCGAGATATTTTAGGACTACTGGCAAAAGGTTAT
GAAAATCAACGCATAGCAGATGAATTATTTATTTCTTTAAAGACAGTGAAAACACATGTGTCCAATATCTTATCAAAGCT
AGAAGTGAGCGATCGTACACAAGCTGTTGTTTATGCTTTCCAACATCACCTTGTCCCACAAGATGACATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A413KQW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.883

98.095

0.529
  degU Bacillus subtilis subsp. subtilis str. 168

38.839

100

0.414