Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   QA586_RS01085 Genome accession   NZ_CP121527
Coordinates   211209..211838 (+) Length   209 a.a.
NCBI ID   WP_278276448.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain 1FSE01     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 206209..216838
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QA586_RS01055 - 206314..206850 (+) 537 WP_001830372.1 hypothetical protein -
  QA586_RS01060 - 207001..207987 (-) 987 WP_002457091.1 aromatic acid exporter family protein -
  QA586_RS01065 map 208161..208916 (+) 756 WP_002457092.1 type I methionyl aminopeptidase -
  QA586_RS01070 - 209074..209460 (+) 387 WP_001830382.1 hypothetical protein -
  QA586_RS01075 liaF 209475..210176 (+) 702 WP_002457093.1 cell wall-active antibiotics response protein LiaF -
  QA586_RS01080 vraS 210173..211219 (+) 1047 WP_001830374.1 sensor histidine kinase Regulator
  QA586_RS01085 vraR 211209..211838 (+) 630 WP_278276448.1 two-component system response regulator VraR Regulator
  QA586_RS01090 - 211895..213073 (-) 1179 WP_001830411.1 YihY/virulence factor BrkB family protein -
  QA586_RS01095 - 213480..213764 (-) 285 WP_001830401.1 YtxH domain-containing protein -
  QA586_RS01100 - 213772..214236 (-) 465 WP_001830437.1 low molecular weight protein-tyrosine-phosphatase -
  QA586_RS01105 - 214377..214592 (+) 216 WP_001830421.1 DUF1128 domain-containing protein -
  QA586_RS01110 - 214594..215835 (+) 1242 WP_002457094.1 aminopeptidase -
  QA586_RS01115 - 215915..216445 (+) 531 WP_001830371.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23610.27 Da        Isoelectric Point: 4.7166

>NTDB_id=812779 QA586_RS01085 WP_278276448.1 211209..211838(+) (vraR) [Staphylococcus epidermidis strain 1FSE01]
MAIKVLFVDDHEMVRIGISIYLSTQEDIEVVGEGASGKDAITKAHELKPDLILMDLLMDDMDGVEATTEIKKDLPQIKVV
MLTSFIEDKEVYRALDSGVDSYILKTTSASDIADAVRKTYEGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=812779 QA586_RS01085 WP_278276448.1 211209..211838(+) (vraR) [Staphylococcus epidermidis strain 1FSE01]
GTGGCGATTAAAGTTTTATTTGTTGATGATCATGAAATGGTAAGAATCGGTATTTCAATCTATCTTTCAACTCAAGAAGA
TATAGAAGTAGTAGGTGAGGGTGCTTCTGGTAAAGATGCTATCACTAAAGCGCATGAGCTAAAACCAGATTTAATATTAA
TGGATTTACTTATGGACGATATGGATGGTGTAGAAGCAACTACTGAAATAAAAAAAGATTTACCTCAAATTAAAGTAGTC
ATGTTAACAAGCTTTATAGAGGATAAAGAAGTTTATCGTGCACTTGATTCTGGAGTAGATAGTTATATTTTAAAGACAAC
AAGTGCAAGTGATATAGCTGACGCTGTGCGTAAAACGTATGAAGGTGAATCAGTATTTGAACCAGAAGTGTTAGTAAAAA
TGCGCAATCGTATGAAAAAACGTGCCGAGCTTTATGAAATGTTGACAGAAAGAGAAATGGAGATCCTATTACTTATAGCT
AAAGGATACTCTAACCAAGAGATTGCAAGCGCCTCTCATATCACCATCAAAACAGTAAAAACTCATGTAAGTAACATACT
AAGTAAATTAGAAGTACAAGATCGAACACAAGCAGTAATATATGCGTTCCAGCATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

94.258

100

0.943
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368